2. Gene
  3. Mapk15 - mitogen-activated protein kinase 15 Gene

Mapk15 - mitogen-activated protein kinase 15 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：丝裂原活化蛋白激酶 15

种属: Rattus norvegicus

同用名: Erk7; ERK-8

基因 ID: 286997 | 基因类型: protein coding

关于 Mapk15

Primary_assembly 7: 107,694,964-107,714,645 forward strand.mRatBN7.2:CM026980.1

This gene has 3 transcripts (splice variants), 197 orthologues, 21 paralogues and is associated with 4 phenotypes. Biased expression in Testes (RPKM 39.2), Lung (RPKM 17.6) and 2 other tissues.

功能概要

预测该基因编码的蛋白可启动 MAP 激酶活性和染色质结合活性。参与多个过程，包括细胞大分子生物合成过程的负调控；蛋白质代谢过程的正向调节；和对雌二醇的反应。位于核内。与人 MAPK15（丝裂原活化蛋白激酶 15）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable MAP kinase activity and chromatin binding activity. Involved in several processes, including negative regulation of cellular macromolecule biosynthetic process; positive regulation of protein metabolic process; and response to estradiol. Located in nucleus. Orthologous to human MAPK15 (mitogen-activated protein kinase 15). [provided by Alliance of Genome Resources, Apr 2022]

Mapk15 基因产物(1)

mRNA Protein Name
NM_173331.2 NP_775453.1 mitogen-activated protein kinase 15
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
9880541 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of DNA replication IMP
IMP: 通过突变表型推断
9891064 RGD
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
12917323 RGD
involved in positive regulation of protein catabolic process IMP
IMP: 通过突变表型推断
12917323 RGD
involved in positive regulation of protein phosphorylation IMP
IMP: 通过突变表型推断
12917323 RGD
involved in positive regulation of protein ubiquitination IMP
IMP: 通过突变表型推断
12917323 RGD
involved in protein autophosphorylation IMP
IMP: 通过突变表型推断
11287416 RGD
involved in protein phosphorylation IDA
IDA: 通过直接分析推断
9891064 RGD
involved in response to estradiol IMP
IMP: 通过突变表型推断
12917323 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
9880541 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

Mapk15 蛋白结构

STKc_MAPK15-like

STKc_MAPK15-like: cd07852 (5 - 343)

  • 0
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  • 500
  • 583 a.a.
蛋白主名 其他名称

mitogen-activated protein kinase 15

ERK-7

MAP kinase 15

MAPK 15

extracellular signal-regulated kinase 7

extracellular signal-regulated kinase 8

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-135906 CK2/ERK8-IN-1 ≥99.0% 否
HY-RS08110 MAPK15 Human Pre-designed siRNA Set A / 否
HY-RS08111 Mapk15 Mouse Pre-designed siRNA Set A / 否
HY-RS08112 Mapk15 Rat Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mapk15 NCBI NCBI:225689
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