2. Gene
  3. MAPK15 - mitogen-activated protein kinase 15 Gene

MAPK15 - mitogen-activated protein kinase 15 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：丝裂原活化蛋白激酶 15

种属: Homo sapiens

同用名: ERK7; ERK8

基因 ID: 225689 | 基因类型: protein coding

关于 MAPK15

Cytogenetic location: 8q24.3 Genomic coordinates (GRCh38): 8:143,716,349-143,722,458 (from NCBI)

This gene has 8 transcripts (splice variants), 1 gene allele, 197 orthologues and 19 paralogues. Biased expression in lung (RPKM 5.3), testis (RPKM 4.6) and 9 other tissues.

功能概要

启用 MAP 激酶活性和染色质结合活性。参与多个过程，包括多巴胺摄取； DNA 代谢过程的正调控；和细胞器组织的调节。位于多种细胞成分中，包括高尔基体；自噬体；和微管组织中心。乳腺癌的生物标志物。 [由基因组资源联盟提供，2022 年 4 月]

Enables MAP kinase activity and chromatin binding activity. Involved in several processes, including dopamine uptake; positive regulation of DNA metabolic process; and regulation of organelle organization. Located in several cellular components, including Golgi apparatus; autophagosome; and microtubule organizing center. Biomarker of breast Cancer. [provided by Alliance of Genome Resources, Apr 2022]

MAPK15 基因产物(10)

mRNA Protein Name
XM_011516927.3 XP_011515229.1 mitogen-activated protein kinase 15 isoform X3
XM_011516925.3 XP_011515227.1 mitogen-activated protein kinase 15 isoform X1
XM_047421568.1 XP_047277524.1 mitogen-activated protein kinase 15 isoform X6
XM_047421567.1 XP_047277523.1 mitogen-activated protein kinase 15 isoform X5
XR_001745493.2
XM_047421566.1 XP_047277522.1 mitogen-activated protein kinase 15 isoform X4
XM_011516928.3 XP_011515230.1 mitogen-activated protein kinase 15 isoform X7
XM_011516926.3 XP_011515228.1 mitogen-activated protein kinase 15 isoform X2
XR_001745494.2
NM_139021.3 NP_620590.2 mitogen-activated protein kinase 15

MAPK15 蛋白结构

Pkinase

Pkinase: Protein kinase domain (15 - 304)

  • 0
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  • 200
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  • 400
  • 500
  • 544 a.a.
蛋白主名 其他名称

mitogen-activated protein kinase 15

ERK-7

ERK-8

MAP kinase 15

MAPK 15

extracellular regulated kinase 8 delta

extracellular signal-regulated kinase 7

extracellular signal-regulated kinase 8

关联疾病

疾病名称 别名
Hemangioma Of Subcutaneous Tissue

Angioma Of The Subcutaneous Tissue

Subcutaneous Haemangioma

Subcutaneous Hemangioma
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-135906 CK2/ERK8-IN-1 ≥99.0% 否
HY-RS08110 MAPK15 Human Pre-designed siRNA Set A / 否
HY-RS08111 Mapk15 Mouse Pre-designed siRNA Set A / 否
HY-RS08112 Mapk15 Rat Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus MAPK15 VGNC VGNC:31217
Canis familiaris MAPK15 VGNC VGNC:42996
Macaca mulatta MAPK15 VGNC VGNC:74570
Mus musculus MAPK15 MGD MGI:2652894
Rattus norvegicus MAPK15 RGD RGD:628675
Others MAPK15 NCBI
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