1. Gene
  2. Arpc3 - actin related protein 2/3 complex, subunit 3 Gene

Arpc3 - actin related protein 2/3 complex, subunit 3 Gene

中文名称:肌动蛋白相关蛋白 2/3 复合物,亚基3

种属: Rattus norvegicus

基因 ID: 288669 | 基因类型: protein coding

关于 Arpc3

Primary_assembly 12: 34,172,780-34,186,651 reverse strand.mRatBN7.2:CM026985.1

This gene has 3 transcripts (splice variants), 286 orthologues and is associated with 2 phenotypes. Biased expression in Thymus (RPKM 834.3), Spleen (RPKM 74.2) and 9 other tissues.

功能概要

预计该基因编码的蛋白是细胞骨架的结构成分。预计有助于肌动蛋白丝结合活性。参与细胞对神经生长因子刺激的反应。位于生长锥前缘。丝状肌动蛋白的一部分。用于研究帕金森病。与人类 ARPC3(肌动蛋白相关蛋白 2/3 复合亚基 3)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to be a structural constituent of Cytoskeleton. Predicted to contribute to actin filament binding activity. Involved in cellular response to nerve growth factor stimulus. Located in growth cone leading edge. Part of filamentous actin. Used to study Parkinson's disease. Orthologous to human ARPC3 (actin related protein 2/3 complex subunit 3). [provided by Alliance of Genome Resources, Apr 2022]

Arpc3 基因产物(1)

mRNA Protein Name
NM_001105933.1 NP_001099403.1 actin-related protein 2月3日 complex subunit 3
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to nerve growth factor stimulus IEP
IEP: 通过表达模式推断
10797548 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell leading edge IDA
IDA: 通过直接分析推断
10209028 RGD
part of filamentous actin IDA
IDA: 通过直接分析推断
10797548 RGD
located in growth cone leading edge IDA
IDA: 通过直接分析推断
10797548 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Arpc3 蛋白结构

P21-Arc

P21-Arc: pfam04062 (0 - 172)

  • 0
  • 100
  • 178 a.a.
蛋白主名 其他名称

actin-related protein 2/3 complex subunit 3

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Arpc3 NCBI NCBI:10094