1. Gene
  2. Smyd2 - SET and MYND domain containing 2 Gene

Smyd2 - SET and MYND domain containing 2 Gene

中文名称:含 SET 和 MYND 域 2

种属: Rattus norvegicus

同用名: HSKM-B

基因 ID: 289372 | 基因类型: protein coding

关于 Smyd2

Primary_assembly 13: 101,425,273-101,466,576 reverse strand.mRatBN7.2:CM026986.1

This gene has 1 transcript (splice variant), 229 orthologues, 5 paralogues and is associated with 3 phenotypes. Biased expression in Muscle (RPKM 828.), Heart (RPKM 47.) and 9 other tissues.

功能概要

预测该基因编码的蛋白可启动 RNA 聚合酶 II 复合物结合活性;组蛋白甲基转移酶活性(H3-K36 特异性);和 p53 结合活性。参与心脏发育。位于细胞质和细胞核中。与人类 SMYD2 同源(SET 和 MYND 结构域包含 2)。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable RNA polymerase II complex binding activity; Histone Methyltransferase activity (H3-K36 specific); and p53 binding activity. Involved in heart development. Located in cytosol and nucleus. Orthologous to human SMYD2 (SET and MYND domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]

Smyd2 基因产物(1)

mRNA Protein Name
NM_206851.1 NP_996733.1 N-lysine methyltransferase SMYD2
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in heart development IEP
IEP: 通过表达模式推断
20305823 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Smyd2 蛋白结构

SET_SMYD2

SET_SMYD2: cd19202 (6 - 268)

zf-MYND

zf-MYND: pfam01753 (51 - 89)

TPR_10

TPR_10: pfam13374 (387 - 421)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 433 a.a.
蛋白主名 其他名称

N-lysine methyltransferase SMYD2

SET and MYND domain-containing protein 2

histone methyltransferase SMYD2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Smyd2 NCBI NCBI:56950