Parp3 - poly (ADP-ribose) polymerase family, member 3 Gene

中文名称：聚 (ADP-核糖) 聚合酶家族，成员 3

种属: Rattus norvegicus

同用名: Adprtl3

关于 Parp3

功能概要

预测该基因编码的蛋白可启动 NAD DNA ADP-核糖基转移酶活性； NAD+ ADP-核糖基转移酶活性；和蛋白质 ADP-核糖基酶活性。预计参与DNA代谢过程；蛋白质 ADP-核糖基化；和 DNA 代谢过程的调节。预计在几个过程的上游或内部起作用，包括 DNA 连接的正向调节；蛋白质定位到双链断裂位点；和调节有丝分裂纺锤体组织。预测位于细胞间桥和核体。预计在核仁和双链断裂位点中具有活性。与人类 PARP3（聚（ADP-核糖）聚合酶家族成员 3）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable NAD DNA ADP-ribosyltransferase activity; NAD+ ADP-ribosyltransferase activity; and protein ADP-ribosylase activity. Predicted to be involved in DNA metabolic process; protein ADP-ribosylation; and regulation of DNA metabolic process. Predicted to act upstream of or within several processes, including positive regulation of DNA ligation; protein localization to site of double-strand break; and regulation of mitotic spindle organization. Predicted to be located in intercellular bridge and nuclear body. Predicted to be active in nucleolus and site of double-strand break. Orthologous to human PARP3 (poly(ADP-ribose) polymerase family member 3). [provided by Alliance of Genome Resources, Apr 2022]