2. Gene
  3. Hcar2 - hydroxycarboxylic acid receptor 2 Gene

Hcar2 - hydroxycarboxylic acid receptor 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：羟基羧酸受体 2

种属: Rattus norvegicus

同用名: Hm74; Hm74b; Pumag; Niacr1; rHM74b; Gpr109a; Gpr109b

基因 ID: 353250 | 基因类型: protein coding

关于 Hcar2

Primary_assembly 12: 32,726,184-32,728,504 forward strand.mRatBN7.2:CM026985.1

This gene has 1 transcript (splice variant), 164 orthologues, 13 paralogues and is associated with 5 phenotypes.

功能概要

该基因编码的蛋白可启动烟酸受体活性。参与脂质分解代谢过程的负调节和脂联素分泌的正调节。预测位于细胞连接和质膜。预计是膜的组成部分。预测在膜中有活性。与人类 HCAR2（羟基羧酸受体 2）和 HCAR3（羟基羧酸受体 3）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables nicotinic acid receptor activity. Involved in negative regulation of lipid catabolic process and positive regulation of Adiponectin secretion. Predicted to be located in cell junction and plasma membrane. Predicted to be integral component of membrane. Predicted to be active in membrane. Orthologous to human HCAR2 (hydroxycarboxylic acid receptor 2) and HCAR3 (hydroxycarboxylic acid receptor 3). [provided by Alliance of Genome Resources, Apr 2022]

Hcar2 基因产物(1)

mRNA Protein Name
NM_181476.2 NP_852141.1 hydroxycarboxylic acid receptor 2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables nicotinic acid receptor activity IDA
IDA: 通过直接分析推断
19141678 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of lipid catabolic process IDA
IDA: 通过直接分析推断
19141678 RGD
involved in positive regulation of adiponectin secretion IDA
IDA: 通过直接分析推断
19141678 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

Hcar2 蛋白结构

7tmA_HCAR1-3

7tmA_HCAR1-3: cd15201 (24 - 301)

7tmA_HCAR1-3

7tmA_HCAR1-3: cd15201 (25 - 51)

7tmA_HCAR1-3

7tmA_HCAR1-3: cd15201 (58 - 83)

7tmA_HCAR1-3

7tmA_HCAR1-3: cd15201 (96 - 126)

7tmA_HCAR1-3

7tmA_HCAR1-3: cd15201 (138 - 160)

7tmA_HCAR1-3

7tmA_HCAR1-3: cd15201 (181 - 210)

7tmA_HCAR1-3

7tmA_HCAR1-3: cd15201 (220 - 250)

7tmA_HCAR1-3

7tmA_HCAR1-3: cd15201 (269 - 294)

  • 0
  • 100
  • 200
  • 300
  • 360 a.a.
蛋白主名 其他名称

hydroxycarboxylic acid receptor 2

G protein-coupled receptor 109B

G protein-coupled receptor Hm74b

G-protein coupled receptor 109

G-protein coupled receptor 109A

G-protein coupled receptor HM74

interferon-gamma inducible gene, Puma-g

niacin receptor 1

nicotinic acid receptor

protein PUMA-G

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06038 HCAR2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-156025 HCAR2 agonist 1 / 否
HY-RS06039 Hcar2 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS06040 Hcar2 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hcar2 NCBI NCBI:338442
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