Melk - maternal embryonic leucine zipper kinase Gene

中文名称：母体胚胎亮氨酸拉链激酶

种属: Rattus norvegicus

关于 Melk

功能概要

预测该基因编码的蛋白编码的蛋白可启动钙离子结合活性；非跨膜蛋白酪氨酸激酶活性；和蛋白丝氨酸/苏氨酸激酶活性。预计参与多个过程，包括细胞内信号转导；凋亡过程的正调控；和蛋白质自身磷酸化。预计在响应氧化应激时在内在凋亡信号通路的上游或内部起作用。预测位于细胞皮层和质膜。与人 MELK（母体胚胎亮氨酸拉链激酶）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable calcium ion binding activity; non-membrane spanning protein tyrosine kinase activity; and protein serine/threonine kinase activity. Predicted to be involved in several processes, including intracellular signal transduction; positive regulation of apoptotic process; and protein autophosphorylation. Predicted to act upstream of or within intrinsic apoptotic signaling pathway in response to oxidative stress. Predicted to be located in cell cortex and plasma membrane. Orthologous to human MELK (maternal embryonic leucine zipper kinase). [provided by Alliance of Genome Resources, Apr 2022]