Prmt8 - protein arginine N-methyltransferase 8 Gene

中文名称：蛋白精氨酸 N-甲基转移酶 8

种属: Mus musculus

同用名: Hrmt1l3; Hrmt1l4

关于 Prmt8

功能概要

预计该基因编码的蛋白具有多种功能，包括 S-腺苷-L-甲硫氨酸结合活性；蛋白质同二聚化活性；和蛋白质-精氨酸 N-甲基转移酶活性。预测参与组蛋白甲基化；肽基-精氨酸甲基化，变成不对称-二甲基精氨酸；和蛋白质同源寡聚化。预计在甲基化上游或甲基化内起作用。预测是质膜细胞质侧的锚定成分。预计在质膜上有活性。以多种结构表达，包括大脑；泌尿生殖系统；心;和肺。与人类 PRMT8（蛋白质精氨酸甲基转移酶 8）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable several functions, including S-adenosyl-L-methionine binding activity; protein homodimerization activity; and protein-arginine N-methyltransferase activity. Predicted to be involved in histone methylation; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine; and protein homooligomerization. Predicted to act upstream of or within methylation. Predicted to be anchored component of the cytoplasmic side of the plasma membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including brain; genitourinary system; heart; and lung. Orthologous to human PRMT8 (protein arginine methyltransferase 8). [provided by Alliance of Genome Resources, Apr 2022]