2. Gene
  3. CXCL16 - C-X-C motif chemokine ligand 16 Gene

CXCL16 - C-X-C motif chemokine ligand 16 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：CXC 基序趋化因子配体 16

种属: Homo sapiens

同用名: SRPSOX; CXCLG16; SR-PSOX

基因 ID: 58191 | 基因类型: protein coding

关于 CXCL16

Cytogenetic location: 17p13.2 Genomic coordinates (GRCh38): 17:4,733,533-4,739,928 (from NCBI)

This gene has 5 transcripts (splice variants) and 88 orthologues. Broad expression in lung (RPKM 40.7), testis (RPKM 23.8) and 24 other tissues.

功能概要

启用趋化因子活性。参与多个过程，包括细胞生长的正调节；对干扰素-γ 的反应；和对肿瘤坏死因子的反应。位于细胞外空间。 COVID-19 和系统性硬皮病的生物标志物。 [由基因组资源联盟提供，2022 年 4 月]

Enables chemokine activity. Involved in several processes, including positive regulation of cell growth; response to interferon-gamma; and response to tumor necrosis factor. Located in extracellular space. Biomarker of COVID-19 and systemic scleroderma. [provided by Alliance of Genome Resources, Apr 2022]

CXCL16 基因产物(2)

mRNA Protein Name
NM_001100812.2 NP_001094282.2 C-X-C motif chemokine 16 isoform 1 precursor
NM_001386809.1 NP_001373738.1 C-X-C motif chemokine 16 isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chemokine activity IDA
IDA: 通过直接分析推断
18373975 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of cell growth IMP
IMP: 通过突变表型推断
18373975 GOA
involved in positive regulation of cell migration IMP
IMP: 通过突变表型推断
18373975 GOA
involved in response to cytokine IDA
IDA: 通过直接分析推断
18373975 GOA
involved in response to tumor necrosis factor IDA
IDA: 通过直接分析推断
18373975 GOA
involved in response to type II interferon IDA
IDA: 通过直接分析推断
18373975 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
18373975 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

C-X-C motif chemokine 16

CXC chemokine ligand 16

重组 CXCL16 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72961 CXCL16 Protein, Human (HEK293, His) Q9H2A7 (N30-T205)/NP_071342.2 (N49-T224) ≥95%
HY-P77910 CXCL16 Protein, Human (HEK293, Fc) Q9H2A7 (N30-T205) ≥95%

关联疾病

疾病名称 别名
Systemic Scleroderma

Scleroderma

Progressive Systemic Sclerosis

Systemic Sclerosis

Scleroderma, Systemic

Scleroderma Syndrome

Dermatosclerosis

Familial Progressive Scleroderma

Progressive Scleroderma

Scleroderma Disease

Scleroderma, Localized

Diffuse Scleroderma

Scleroderma, Familial Progressive
Systemic Lupus Erythematosus

Lupus Nephritis

SLE

Disseminated Lupus Erythematosus

Systemic Lupus Erythematosus, Susceptibility To

Lupus Erythematosus, Systemic

Lupus Nephritis, Susceptibility To

Libman-Sacks Disease

Systemic Lupus Erythematosus Susceptibility To

Sle - Lupus Erythematosus, Systemic

Le Syndrome

Lupus

Lupus Erythematosus Systemic

Lupus Erythematosus, Systemic, Susceptibility To

Lupus Vulgaris

Lupus Erythematosus, Discoid

Lupus Erythematosus

Systemic Lupus Erythematosus Nos

Sle - [Systemic Lupus Erythematosus]
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-122197 ML339 Antagonist 99.88% 否
HY-RS03389 CXCL16 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta CXCL16 VGNC VGNC:71422
Bos taurus CXCL16 VGNC VGNC:27851
Mus musculus CXCL16 MGD MGI:1932682
Rattus norvegicus CXCL16 RGD RGD:1562928
Felis catus CXCL16 VGNC VGNC:61298
Canis familiaris CXCL16 VGNC VGNC:53326
Others CXCL16 NCBI
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