1. Gene
  2. PBLD - phenazine biosynthesis like protein domain containing Gene

PBLD - phenazine biosynthesis like protein domain containing Gene

中文名称:含吩嗪生物合成样蛋白结构域

种属: Homo sapiens

同用名: MAWBP; MAWDBP; HEL-S-306

基因 ID: 64081 | 基因类型: protein coding

关于 PBLD

Cytogenetic location: 10q21.3 Genomic coordinates (GRCh38): 10:68,282,660-68,332,928 (from NCBI)

This gene has 7 transcripts (splice variants) and 223 orthologues. Biased expression in kidney (RPKM 94.0), duodenum (RPKM 62.5) and 5 other tissues.

功能概要

实现相同的蛋白质结合活性。参与维护胃肠上皮; SMAD 蛋白信号转导的负调控;和转化生长因子β受体信号通路的负调控。位于细胞质中。 [由基因组资源联盟提供,2022 年 4 月]

Enables identical protein binding activity. Involved in maintenance of gastrointestinal epithelium; negative regulation of SMAD protein signal transduction; and negative regulation of transforming growth factor beta receptor signaling pathway. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

PBLD 基因产物(2)

mRNA Protein Name
NM_001033083.2 NP_001028255.1 phenazine biosynthesis-like domain-containing protein isoform b
NM_022129.4 NP_071412.2 phenazine biosynthesis-like domain-containing protein isoform a

PBLD 蛋白结构

PhzC-PhzF

PhzC-PhzF: Phenazine biosynthesis-like protein (9 - 284)

  • 0
  • 100
  • 200
  • 288 a.a.
蛋白主名 其他名称

phenazine biosynthesis-like domain-containing protein

MAWD-binding protein

PBLD 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
PBLD P30039 CCDC184 Homo sapiens Q52MB2
Y2H Prey Pooling
32296183
种属内
PBLD P30039 CCDC184 Homo sapiens Q52MB2
Validated Y2H
32296183
种属内
PBLD P30039 CCDC184 Homo sapiens Q52MB2
Y2H Array
25416956
种属内
PBLD P30039 CCDC184 Homo sapiens Q52MB2
Y2H Array
32296183
种属内
PBLD P30039 BEND7 Homo sapiens Q8N7W2-2
Y2H Array
32296183
种属内
PBLD P30039 BEND7 Homo sapiens Q8N7W2-2
Validated Y2H
32296183
种属内
PBLD P30039 BEND7 Homo sapiens Q8N7W2-2
Y2H Prey Pooling
32296183
种属内
PBLD P30039 AMOT Homo sapiens A2BDD9
Y2H Array
32296183
种属内
PBLD P30039 AMOT Homo sapiens A2BDD9
Y2H Prey Pooling
32296183
种属内
PBLD P30039 VAC14 Homo sapiens Q08AM6
Validated Y2H
32296183
种属内
PBLD P30039 VAC14 Homo sapiens Q08AM6
Y2H Prey Pooling
32296183
种属内
PBLD P30039 VAC14 Homo sapiens Q08AM6
Y2H Array
32296183
种属内
PBLD P30039 EFHC2 Homo sapiens Q5JST6
Y2H Prey Pooling
25416956
种属内
PBLD P30039 EFHC2 Homo sapiens Q5JST6
Validated Y2H
25416956
种属内
PBLD P30039 EFHC2 Homo sapiens Q5JST6
Y2H Prey Pooling
32296183
种属内
PBLD P30039 EFHC2 Homo sapiens Q5JST6
Validated Y2H
32296183
种属内
PBLD P30039 EFHC2 Homo sapiens Q5JST6
Y2H Array
32296183
种属内
PBLD P30039 TRIP13 Homo sapiens Q15645
Validated Y2H
25416956
种属内
PBLD P30039 TRIP13 Homo sapiens Q15645
Y2H Array
25416956
种属内
PBLD P30039 ZRANB1 Homo sapiens Q9UGI0
Anti Tag CoIP
33961781
种属内
PBLD P30039 ZRANB1 Homo sapiens Q9UGI0
Anti Tag CoIP
28514442
种属内
PBLD P30039 ZRANB1 Homo sapiens Q9UGI0
Validated Y2H
32296183
种属内
PBLD P30039 ZRANB1 Homo sapiens Q9UGI0
Y2H Prey Pooling
32296183
种属内
PBLD P30039 ZRANB1 Homo sapiens Q9UGI0
Y2H Array
32296183
种属内
PBLD P30039 TCF4 Homo sapiens P15884
Y2H Array
25416956
种属内
PBLD P30039 LNX1 Homo sapiens Q8TBB1
Y2H Array
25416956
种属内
PBLD P30039 GRAP2 Homo sapiens O75791
Y2H Prey Pooling
32296183
种属内
PBLD P30039 GRAP2 Homo sapiens O75791
Y2H Array
32296183
种属内
PBLD P30039 PBLD Homo sapiens P30039
Validated Y2H
32296183
种属内
PBLD P30039 PBLD Homo sapiens P30039
Y2H Array
25416956
种属内
PBLD P30039 PBLD Homo sapiens P30039
Y2H Array
32296183
种属内
PBLD P30039 PBLD Homo sapiens P30039
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 PBLD 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71144 PBLD Protein, Human (His) P30039-1(M1-A288) ≥95%

关联疾病

疾病名称 别名
Retinal Arteries, Tortuosity Of

Retinal Arterial Tortuosity

Retinal Hemorrhage With Vascular Tortuosity

RATOR

Tortuosity Of Retinal Arteries

Retinal Arteriolar Tortuosity

Familial Isolated Retinal Arterial Tortuosity

Tortuosity, Arteries, Retinal

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus PBLD MGD MGI:1915621
Rattus norvegicus PBLD RGD RGD:621263
Felis catus PBLD VGNC VGNC:64055
Macaca mulatta PBLD VGNC VGNC:75669
Bos taurus PBLD VGNC VGNC:32605
Canis familiaris PBLD VGNC VGNC:44284
Others PBLD NCBI