1. Gene
  2. Robo4 - roundabout guidance receptor 4 Gene

Robo4 - roundabout guidance receptor 4 Gene

种属: Mus musculus

同用名: 1200012D01Rik

基因 ID: 74144 | 基因类型: protein coding

关于 Robo4

功能概要

Enables signaling receptor activity. Acts upstream of or within negative regulation of cell migration. Located in external side of plasma membrane. Is expressed in several structures, including forebrain; genitourinary system; neural retina; submandibular gland; and vascular system. Human ortholog(s) of this gene implicated in aortic valve disease 3. Orthologous to human ROBO4 (roundabout guidance receptor 4). [provided by Alliance of Genome Resources, Apr 2022]

Robo4 基因产物(2)

mRNA Protein Name
NM_001309390.2 NP_001296319.2 roundabout homolog 4 isoform 1 precursor
NM_028783.4 NP_083059.3 roundabout homolog 4 isoform 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12941633 MGI
enables signaling receptor activity IDA
IDA: 通过直接分析推断
12941633 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of blood vessel endothelial cell migration IDA
IDA: 通过直接分析推断
12941633 MGI
acts upstream of or within negative regulation of blood vessel endothelial cell migration IDA
IDA: 通过直接分析推断
12941633 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
12941633 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

roundabout homolog 4

Magic roundabout

重组 Robo4 蛋白

目录号 产品名 蛋白编号 纯度
HY-P78031 ROBO4 Protein, Mouse (453a.a, HEK293, His) Q8C310-1 (L28-W480) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Robo4 NCBI NCBI:54538