2. Gene
  3. Prmt3 - protein arginine methyltransferase 3 Gene

Prmt3 - protein arginine methyltransferase 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：蛋白质精氨酸甲基转移酶 3

种属: Rattus norvegicus

同用名: Hrmt1l3

基因 ID: 89820 | 基因类型: protein coding

关于 Prmt3

Primary_assembly 1: 99,492,724-99,579,435 forward strand.mRatBN7.2:CM026974.1

This gene has 2 transcripts (splice variants), 205 orthologues, 10 paralogues and is associated with 2 phenotypes. Biased expression in Muscle (RPKM 111.1), Spleen (RPKM 18.2) and 9 other tissues.

功能概要

该基因编码的蛋白可启动修饰的氨基酸结合活性和蛋白质-精氨酸 omega-N 不对称甲基转移酶活性。参与树突棘形态发生和肽基-精氨酸甲基化，形成不对称-二甲基精氨酸。位于细胞质中。哮喘的生物标志物。与人类 PRMT3（蛋白质精氨酸甲基转移酶 3）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables modified amino acid binding activity and protein-arginine omega-N asymmetric methyltransferase activity. Involved in dendritic spine morphogenesis and peptidyl-arginine methylation, to asymmetrical-dimethyl arginine. Located in cytoplasm. Biomarker of asthma. Orthologous to human PRMT3 (protein arginine methyltransferase 3). [provided by Alliance of Genome Resources, Apr 2022]

Prmt3 基因产物(1)

mRNA Protein Name
NM_053557.1 NP_446009.1 protein arginine N-methyltransferase 3

Prmt3 蛋白结构

AdoMet_MTases

AdoMet_MTases: cd02440 (255 - 355)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 528 a.a.
蛋白主名 其他名称

protein arginine N-methyltransferase 3

heterogeneous nuclear ribonucleoprotein methyltransferase-like 3

heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3

protein arginine N-methyltransferase 3(hnRNP methyltransferase S. cerevisiae)-like 3

相关产品

Pre-clinical Phase
生物活性分子 (9)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-19615 MS023 Inhibitor 99.73% 否
HY-19715 SGC707 Inhibitor 98.08% 否
HY-19615B MS023 dihydrochloride Inhibitor 99.78% 否
HY-128717B GSK3368715 trihydrochloride Inhibitor / 否
HY-146810 PRMT4-IN-1 Inhibitor / 否
HY-110158 UNC2327 Inhibitor 99.70% 否
HY-159728 PROTAC PRMT3 degrader 1 Degrader / 否
HY-161334 CARM1-IN-4 Inhibitor / 否
HY-159732 PRMT3-IN-4 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Prmt3 NCBI NCBI:10196
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