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  2. Prmt3 - protein arginine methyltransferase 3 Gene

Prmt3 - protein arginine methyltransferase 3 Gene

中文名称:蛋白质精氨酸甲基转移酶 3

种属: Rattus norvegicus

同用名: Hrmt1l3

基因 ID: 89820 | 基因类型: protein coding

关于 Prmt3

Primary_assembly 1: 99,492,724-99,579,435 forward strand.mRatBN7.2:CM026974.1

This gene has 2 transcripts (splice variants), 205 orthologues, 10 paralogues and is associated with 2 phenotypes. Biased expression in Muscle (RPKM 111.1), Spleen (RPKM 18.2) and 9 other tissues.

功能概要

该基因编码的蛋白可启动修饰的氨基酸结合活性和蛋白质-精氨酸 omega-N 不对称甲基转移酶活性。参与树突棘形态发生和肽基-精氨酸甲基化,形成不对称-二甲基精氨酸。位于细胞质中。哮喘的生物标志物。与人类 PRMT3(蛋白质精氨酸甲基转移酶 3)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables modified amino acid binding activity and protein-arginine omega-N asymmetric methyltransferase activity. Involved in dendritic spine morphogenesis and peptidyl-arginine methylation, to asymmetrical-dimethyl arginine. Located in cytoplasm. Biomarker of asthma. Orthologous to human PRMT3 (protein arginine methyltransferase 3). [provided by Alliance of Genome Resources, Apr 2022]

Prmt3 基因产物(1)

mRNA Protein Name
NM_053557.1 NP_446009.1 protein arginine N-methyltransferase 3
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables modified amino acid binding IDA
IDA: 通过直接分析推断
10899106 RGD
enables protein-arginine N-methyltransferase activity IDA
IDA: 通过直接分析推断
9642256 RGD
enables protein-arginine omega-N asymmetric methyltransferase activity IDA
IDA: 通过直接分析推断
9642256 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in dendritic spine morphogenesis IMP
IMP: 通过突变表型推断
20647003 RGD
involved in peptidyl-arginine methylation IDA
IDA: 通过直接分析推断
10899106 RGD
involved in peptidyl-arginine methylation, to asymmetrical-dimethyl arginine IDA
IDA: 通过直接分析推断
9642256 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Prmt3 蛋白结构

AdoMet_MTases

AdoMet_MTases: cd02440 (255 - 355)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 528 a.a.
蛋白主名 其他名称

protein arginine N-methyltransferase 3

heterogeneous nuclear ribonucleoprotein methyltransferase-like 3

heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3

protein arginine N-methyltransferase 3(hnRNP methyltransferase S. cerevisiae)-like 3

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Prmt3 NCBI NCBI:10196