2. Anti-infection
  3. HCV
  4. GS-6620

GS-6620是一种有效的、选择性的泛型 HCV 抑制剂，可抑制基因型1 ~ 6的HCV复制子 (EC50: 0.048 ~ 0.68 μM)。GS-6620对其他病毒的抑制作用有限，对密切相关的牛病毒性腹泻病毒(EC50， 1.5 μM) 只有部分抑制作用。

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GS-6620 Chemical Structure

GS-6620 Chemical Structure

CAS No. : 1350735-70-4

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规格 价格 是否有货 数量
1 mg ￥16200
In-stock
5 mg   询价  
10 mg   询价  

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Customer Review

GS-6620 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

GS-6620 is potent and selective pangenotype HCV inhibitor against HCV replicons of genotypes 1 to 6 (EC50: 0.048 to 0.68 μM). GS-6620 shows limited activities against other viruses, maintaining only some of its activity against the closely related bovine viral diarrhea virus (EC50, 1.5 μM)[1].

IC50 & Target

IC50: 48-680 nM (HCV replicons of genotypes 1 to 6)[1]
细胞效力
(Cellular Effect)
Cell Line Type Value Description References
Huh-7 EC50
0.61 μM
Compound: 16
Antiviral activity against HCV genotype 1b infected in human HuH7 cells assessed as inhibition of viral replication after 3 days by luminescence assay
Antiviral activity against HCV genotype 1b infected in human HuH7 cells assessed as inhibition of viral replication after 3 days by luminescence assay
[PMID: 23547794]
Huh-7 CC50
47 μM
Compound: 16
Cytotoxicity against human HuH7 cells after 3 days by fluorescence assay
Cytotoxicity against human HuH7 cells after 3 days by fluorescence assay
[PMID: 23547794]
分子量

644.61

Formula

C29H37N6O9P
CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献

GS-6620 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GS-66201350735-70-4GS6620GS 6620HCVHepatitis C virusInhibitorinhibitorinhibit

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产品名称：
GS-6620
目录号：
HY-12633
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