2. Cell Cycle/DNA Damage Metabolic Enzyme/Protease
  3. HSP
  4. HM03 trihydrochloride

HM03 trihydrochloride是一种有效的选择性的热休克 70 kDa 蛋白 5, HSPA5 (也称为 Bip，Grp78) 抑制剂，具有抗肿瘤活性。

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HM03 trihydrochloride Chemical Structure

HM03 trihydrochloride Chemical Structure

CAS No. : 1082532-95-3

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HM03 trihydrochloride 的其他形式现货产品:

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Other Forms of HM03 trihydrochloride:

HM03 trihydrochloride 相关抗体

Top Publications Citing Use of Products

查看 HSP 亚型特异性产品:

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HSP40 HSP70 HSP90 HSP105 HSF1 HSP HSPA5

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

HM03 trihydrochloride is a potent and selective HSPA5 (Heat shock 70kDa protein 5, also known as Bip, Grp78) inhibitor. HM03 trihydrochloride has anticancer activity[1].

体外研究
(In Vitro)

HM03 trihydrochloride (0.1-50 μM; 72 hours) exhibits over 50% inhibition at 25 µM concentration in HCT116 cells[1].
HM03 trihydrochloride forms more binding interactions with HSPA5 and HSPA9 than with the other HSP70 proteins[1].
HM03 trihydrochloride exhibits promising inhibition activities from cancer cell viability and tumor inhibition assays[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

HM03 trihydrochloride 相关抗体:
分子量

572.35

Formula

C26H30Cl4N4O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

HM03 trihydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HM03 trihydrochloride1082532-95-3HSPHeat shock proteinsheatshockproteincancercellHCT116tumorInhibitorinhibitorinhibit

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产品名称：
HM03 trihydrochloride
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HY-125974A
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