2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Isotetrandrine

Isotetrandrine 是 Stephania tetrandra 中的活性成分。

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Isotetrandrine Chemical Structure

Isotetrandrine Chemical Structure

CAS No. : 477-57-6

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Isotetrandrine 相关抗体

Top Publications Citing Use of Products

MCE 顾客使用本产品发表的 1 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Isotetrandrine is a bioactive component in Stephania tetrandra[1].

IC50 & Target

Human Endogenous Metabolite

 

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A-431 ED50
8.4 μg/mL
Compound: 4
Cytotoxicity against human A431 cells after 3 days by sulforhodamine B assay
Cytotoxicity against human A431 cells after 3 days by sulforhodamine B assay
[PMID: 8450319]
HT-1080 ED50
11 μg/mL
Compound: 4
Cytotoxicity against human HT1080 cells after 3 days by sulforhodamine B assay
Cytotoxicity against human HT1080 cells after 3 days by sulforhodamine B assay
[PMID: 8450319]
KB ED50
10600 nM
Compound: 18
Cytotoxicity against human KB cells after 72 hrs by SRB assay
Cytotoxicity against human KB cells after 72 hrs by SRB assay
[PMID: 9917283]
KB ED50
6.6 μg/mL
Compound: 4
Cytotoxicity against human KB cells after 3 days by sulforhodamine B assay
Cytotoxicity against human KB cells after 3 days by sulforhodamine B assay
[PMID: 8450319]
KB-V1 ED50
1.5 μg/mL
Compound: 4
Cytotoxicity against human KBV1 cells after 3 days by sulforhodamine B assay
Cytotoxicity against human KBV1 cells after 3 days by sulforhodamine B assay
[PMID: 8450319]
LNCaP ED50
9.4 μg/mL
Compound: 4
Cytotoxicity against human LNCAP cells after 3 days by sulforhodamine B assay
Cytotoxicity against human LNCAP cells after 3 days by sulforhodamine B assay
[PMID: 8450319]
P388 ED50
5.6 μg/mL
Compound: 4
Cytotoxicity against mouse P388 cells after 2 days by sulforhodamine B assay
Cytotoxicity against mouse P388 cells after 2 days by sulforhodamine B assay
[PMID: 8450319]
SK-MEL-2 ED50
19.5 μg/mL
Compound: 4
Cytotoxicity against human SK-MEL-2 cells after 3 days by sulforhodamine B assay
Cytotoxicity against human SK-MEL-2 cells after 3 days by sulforhodamine B assay
[PMID: 8450319]
ZR-75-1 ED50
5 μg/mL
Compound: 4
Cytotoxicity against human ZR-75-1 cells after 3 days by sulforhodamine B assay
Cytotoxicity against human ZR-75-1 cells after 3 days by sulforhodamine B assay
[PMID: 8450319]
体外研究
(In Vitro)

Fangchi, derived from the rhizoma of S. acutum and the radix of S. tetrandra and S. acutum, has been widely used for the treatment of rheumatic arthritis[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Isotetrandrine 相关抗体:
分子量

622.75

Formula

C38H42N2O6
CAS 号
性状

固体

颜色

White to light yellow

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

纯度 & 产品资料

纯度: ≥97.0%

COA (178 KB) HNMR (161 KB)

产品使用指南 (1538 KB)
参考文献

Isotetrandrine 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Isotetrandrine477-57-6Endogenous MetaboliteInhibitorinhibitorinhibit

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