1. GPCR/G Protein Neuronal Signaling
  2. Cannabinoid Receptor
  3. KM-233

KM-233 是一种典型的大麻素,具有良好的血脑屏障穿透性。KM-233 对 CB2 受体具有相对于 THC 的选择性亲和性。KM-233 能有效降低 U87 胶质瘤的肿瘤负担,可用于胶质瘤的研究。

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KM-233 Chemical Structure

KM-233 Chemical Structure

CAS No. : 628263-22-9

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规格 价格 是否有货 数量
1 mg ¥1318
3 - 4 周
5 mg   询价  
10 mg   询价  

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查看 Cannabinoid Receptor 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

KM-233 is a classical cannabinoid with good blood brain barrier penetration. KM-233 possesses a selective affinity for the CB2 receptors relative to THC. KM-233 is effective at reducing U87 glioma tumor burden, and can be used for glioma research[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
LN-229 EC50
2.63 μM
Compound: 2
Cytotoxicity against human LN229 cells assessed as cell death after 18 hrs
Cytotoxicity against human LN229 cells assessed as cell death after 18 hrs
[PMID: 18524604]
T98G EC50
4.68 μM
Compound: 2
Cytotoxicity against human T98G cells assessed as cell death after 18 hrs
Cytotoxicity against human T98G cells assessed as cell death after 18 hrs
[PMID: 18524604]
U-87MG ATCC EC50
3.08 μM
Compound: 2
Cytotoxicity against human U87 cells by side flank model relative to control
Cytotoxicity against human U87 cells by side flank model relative to control
[PMID: 18524604]
分子量

362.50

Formula

C25H30O2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
KM-233
目录号:
HY-123410
需求量: