2. Academic Validation
  3. Three cyclooctapeptides and one glycoside from Microtoena prainiana

Three cyclooctapeptides and one glycoside from Microtoena prainiana

  • J Nat Prod. 2004 Jun;67(6):978-82. doi: 10.1021/np040021x.
Chong-Qian Li 1,  Bo-Gang Li,  Hua-Yi Qi,  Qi-Lin Li,  Feng-Peng Wang,  Guo-Lin Zhang
Affiliations

Affiliation

  • 1 West China School of Pharmacy, Sichuan University, Chengdu 610041, People's Republic of China.
PMID: 15217277 DOI: 10.1021/np040021x
Abstract

Three new cyclic octapeptides, microtoenins A-C (1-3), and a new glycoside, 3'''-O-methylcrenatoside (4), along with several known compounds, were isolated from the ethanolic extract of the stems of Microtoena prainiana. Their structures were determined by spectral and chemical evidence. At a concentration of 0.01 mg/mL, 3'''-O-methylcrenatoside (4), crenatoside (5), and isocrenatoside (6) inhibited angiotensin converting Enzyme (ACE) activity by more than 30%.

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