Prebiotic stachyose inhibits PRDX5 activity and castration-resistant prostate cancer development

Affiliations

• 1 MOE Medical Basic Research Innovation Center for Gut Microbiota and Chronic Diseases, Wuxi School of Medicine, Jiangnan University, Wuxi, China; School of Food Science and Technology, Jiangnan University, Wuxi, China.
• 2 MOE Medical Basic Research Innovation Center for Gut Microbiota and Chronic Diseases, Wuxi School of Medicine, Jiangnan University, Wuxi, China.
• 3 First Affiliated Hospital of Nanjing Medical University, Nanjing Medical University, Nanjing, China; Affiliated Hospital of Jiangnan University, Jiangnan University, Wuxi, China.
• 4 Affiliated Hospital of Jiangnan University, Jiangnan University, Wuxi, China.
• 5 College of Pharmacy, Pharmaceutical Series, China Pharmaceutical University, Nanjing, China.
• 6 Jiangnan University Medical Center, Jiangnan University, Wuxi, China.
• 7 Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology & School of Life Sciences and Health Engineering, Jiangnan University, Wuxi, China.
• 8 Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore; Nanomedicine Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
• 9 Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
• 10 Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
• 11 Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore, Singapore.
• 12 Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore; Division of Hematology/Oncology, Cedars-Sinai Medical Center, UCLA School of Medicine, CA, Los Angeles, USA.
• 13 First Affiliated Hospital of Nanjing Medical University, Nanjing Medical University, Nanjing, China. Electronic address: drc_lijie@126.com.
• 14 Affiliated Hospital of Jiangnan University, Jiangnan University, Wuxi, China. Electronic address: miniao1984@163.com.
• 15 MOE Medical Basic Research Innovation Center for Gut Microbiota and Chronic Diseases, Wuxi School of Medicine, Jiangnan University, Wuxi, China; School of Food Science and Technology, Jiangnan University, Wuxi, China. Electronic address: yqchen@jiangnan.edu.cn.