4-(Pyrazolyl)benzenesulfonamide Ureas as Carbonic Anhydrases Inhibitors and Hypoxia-Mediated Chemo-Sensitizing Agents in Colorectal Cancer Cells

Affiliations

• 1 Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh 33516, Egypt.
• 2 Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Pharos University in Alexandria, Canal El Mahmoudia Street, Alexandria 21648, Egypt.
• 3 Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo 11829, Egypt.
• 4 Sydney Pharmacy School, The University of Sydney, Sydney, New South Wales 2006, Australia.
• 5 Department NEUROFARBA─Pharmaceutical and Nutraceutical Section, University of Firenze, via Ugo Schiff 6, Sesto Fiorentino I-50019, Firenze, Italy.
• 6 Department of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Halle (Saale) D-06120, Germany.
• 7 Department of Medicinal Chemistry, Institute of Pharmacy, Martin-Luther-University of Halle-Wittenberg, Halle (Saale) D-06120, Germany.
• 8 Department of Chemistry, College of Science, Princess Nourah Bint Abdulrahman University, Riyadh 11564, Saudi Arabia.
• 9 Applied Organic Chemistry Department, National Research Center, Dokki, Giza 12622, Cairo, Egypt.
• 10 School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales 2052, Australia.