1. 多肽产品
  2. 多肽及其衍生物
  3. 肽表位
  4. Myelin Basic Protein (1-11)

Myelin Basic Protein (1-11) 是髓鞘碱性蛋白 (MBP) 的致脑炎表位。Myelin Basic Protein (1-11) 可用于诱导实验性自身免疫性脑脊髓炎 (EAE)。

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Custom Peptide Synthesis

Myelin Basic Protein (1-11) Chemical Structure

Myelin Basic Protein (1-11) Chemical Structure

CAS No. : 106128-98-7

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Myelin Basic Protein (1-11) is an encephalitogenic epitope of myelin basic protein (MBP). Myelin Basic Protein (1-11) can be used for induction of experimental autoimmune encephalomyelitis (EAE)[1][2].

体外研究
(In Vitro)

Myelin Basic Protein (1-11) (0-10 μg/mL) 刺激 MBP-TCR CD4 T 细胞产生 IL-2[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Myelin Basic Protein (1-11) (100 μg/mL)-pulsed DC 细胞 (i.p.) 在转移到受照射的 B10.PL 小鼠体内时会诱导实验性自身免疫性脑脊髓炎 (EAE)[1]
Myelin Basic Protein (1-11) (100 μg,腹腔注射) 诱导成年小鼠对 MBP 的耐受性并预防 MBP 诱导的 EAE[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1293.39

Formula

C52H88N22O17

CAS 号
Sequence Shortening

Ac-ASQKRPSQRHG

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Myelin Basic Protein (1-11) 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Myelin Basic Protein (1-11)
目录号:
HY-P3073
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