2. PROTAC
  3. PROTAC Linkers
  4. NH2-PEG8-OH

NH2-PEG8-OH 是一种 PROTAC linker，属于 PEG 类。NH2-PEG8-OH 可用于合成PROTAC分子。

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NH2-PEG8-OH Chemical Structure

NH2-PEG8-OH Chemical Structure

CAS No. : 352439-37-3

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NH2-PEG8-OH 相关抗体

Top Publications Citing Use of Products

查看 PROTAC Linkers 亚型特异性产品:

查看所有亚型
PEG Linkers Alkyl-Chain Linkers Alkyl/ether Linkers

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

NH2-PEG8-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

NH2-PEG8-OH 相关抗体:
分子量

369.45

Formula

C16H35NO8
CAS 号
性状

固液混合物

颜色

Colorless to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

纯度 & 产品资料

纯度: ≥97.0%

COA (276 KB) HNMR (117 KB) MS (270 KB)

产品使用指南 (1538 KB)
参考文献

NH2-PEG8-OH 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NH2-PEG8-OH352439-37-3PROTAC LinkersInhibitorinhibitorinhibit

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产品名称：
NH2-PEG8-OH
目录号：
HY-130200
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