2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  3. EGFR
  4. Olmutinib hydrochloride

Olmutinib hydrochloride  (Synonyms: HM61713 hydrochloride; BI 1482694 hydrochloride)

目录号: HY-19730A
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摩尔计算器

Olmutinib hydrochloride 是口服有效的，不可逆的第三代 EGFR 酪氨酸激酶抑制剂，其与激酶结构域附近的半胱氨酸残基结合。Olmutinib hydrochloride 可用于非小细胞肺癌的研究。

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Olmutinib hydrochloride Chemical Structure

Olmutinib hydrochloride Chemical Structure

CAS No. : 1842366-97-5

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Olmutinib hydrochloride 的其他形式现货产品:

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Olmutinib hydrochloride 相关抗体

Top Publications Citing Use of Products

    Olmutinib hydrochloride purchased from MCE. Usage Cited in: Acta Pharm Sin B. 2018 Jul;8(4):563-574.  [Abstract]

    The protein levels of ABCG2 in MDR cells after different concentrations Olmutinib stimulation for 48 h are measured by Western blot analysis (GAPDH as loading control).

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    EGFR/ErbB1/HER1 ErbB2/HER2 ErbB3/HER3 ErbB4/HER4

    • 生物活性

    • 纯度 & 产品资料

    • 参考文献

    生物活性

    Olmutinib hydrochloride is an orally active and irreversible third EGFR tyrosine kinase inhibitor that binds to a cysteine residue near the kinase domain. Olmutinib hydrochloride is used for NSCLC[1][2].

    分子量

    559.51

    Formula

    C26H28Cl2N6O2S
    CAS 号
    运输条件

    Room temperature in continental US; may vary elsewhere.
    储存方式

    Please store the product under the recommended conditions in the Certificate of Analysis.
    纯度 & 产品资料
    参考文献

    Olmutinib hydrochloride 相关分类

    • 摩尔计算器

    • 稀释计算器

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    The dilution calculator equation

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    × = ×
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    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Olmutinib1842366-97-5HM61713BI 1482694HM 61713HM-61713BI1482694BI-1482694EGFREpidermal growth factor receptorErbB-1HER1Inhibitorinhibitorinhibit

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