2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  3. EGFR
  4. PD 173955 analog 1

PD 173955 analog 1 (Compound 26) 是 PD 173955 (HY-10395) 的类似物。PD 173955 analog 1 是 EGFR kinase 的抑制剂，具有抗肿瘤和毒理学特性。PD 173955 analog 1 的计算机模拟 IC50 为 0.19 μM。

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PD 173955 analog 1 Chemical Structure

PD 173955 analog 1 Chemical Structure

CAS No. : 185039-99-0

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PD 173955 analog 1 相关抗体

Top Publications Citing Use of Products

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EGFR/ErbB1/HER1 ErbB2/HER2 ErbB3/HER3 ErbB4/HER4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PD 173955 analog 1 (Compound 26) is an analog of PD 173955 (HY-10395). PD 173955 analog 1 is an inhibitor for EGFR kinase, which exhibits antitumor and toxicological properties. PD 173955 analog 1 exhibits an in silico IC50 of 0.19 μM[1].

IC50 & Target

EGFR

0.19 μM (IC50)

分子量

441.27

Formula

C21H14Cl2N4O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

PD 173955 analog 1 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PD 173955 analog 1185039-99-0EGFREpidermal growth factor receptorErbB-1HER1Inhibitorinhibitorinhibit

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PD 173955 analog 1
目录号：
HY-18298
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