1. 重组蛋白
  2. CD Antigens Receptor Proteins
  3. Stem Cell CD Proteins Platelet CD Proteins
  4. TPO-R/CD110
  5. C-MPL 蛋白, Cynomolgus (HEK293, His)

C-MPL 蛋白, Cynomolgus (HEK293, His)

目录号: HY-P700977
COA 产品使用指南

C-MPL 蛋白是 I 型细胞因子受体家族的关键成员,对于介导细胞对各种细胞因子的反应至关重要。其研究增强了我们对细胞信号传导的理解,为造血疾病和免疫疾病的治疗干预提供了潜在的应用。C-MPL 蛋白, Cynomolgus (HEK293, His) 是重组的 C-MPL 蛋白,由 HEK293 表达,带有 C-His 标签。C-MPL 蛋白, Cynomolgus (HEK293, His) 全长 468 个氨基酸,分子量为 60-70 kDa。

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     可免费申领三个不同产品的试用装。

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规格 价格 是否有货 数量
20 μg ¥1750 In-stock
50 μg ¥2800 In-stock
100 μg   询价  

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  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

C-MPL protein is a key member of the type I cytokine receptor family and is essential for mediating cellular responses to various cytokines. Its research enhances our understanding of cell signaling, providing potential applications for therapeutic intervention in hematopoietic disorders and immune disorders. C-MPL Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived C-MPL protein, expressed by HEK293 , with C-His labeled tag. The total length of C-MPL Protein, Cynomolgus (HEK293, His) is 468 a.a., with molecular weight of 60-70 kDa.

研究背景

C-MPL 蛋白是 I 型细胞因子受体家族的关键成员,特别属于 1 型亚家族,强调了其在介导细胞对各种细胞因子的反应中的关键作用。作为该受体家族的一部分,C-MPL 可能与相关受体具有保守的结构和功能特征,强调其参与转导特定 I 型细胞因子的信号。I 型细胞因子受体家族的分类强调了其在更广泛的细胞信号传导背景下的特定名称,从而深入了解其对造血和免疫调节的独特贡献。C-MPL 的研究有助于我们了解其在生理过程中的作用,为造血障碍和免疫失调相关疾病的治疗干预提供了潜在的应用。对 C-MPL 作用的进一步探索有望增强我们对其对正常细胞功能和病理状况的贡献的了解。

生物活性

Immobilized Cynomolgus c-MPL, His Tag at 0.5 μg/mL (100 μl/well) on the plate. Dose response curve for Anti-C-MPL Antibody, hFc Tag with the EC50 of ≤12.7 ng/mL determined by ELISA.

种属

Cynomolgus

表达系统

HEK293

标签

C-His

蛋白编号

A0A2K5UGC7 (Q22-T489)

基因 ID

/

蛋白结构
N-term
C-MPL (Q22-T489)
Accession # A0A2K5UGC7
His
C-term
同用名
TPO-R; CD110; MPL; c-Mpl; MPLV; K12
分子量

60-70 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

性状

溶液.

组分

Supplied as a 0.22μm filtered solution of 20mM Tris, 500mM NaCl, 3 mM DTT, 10% glycerol, pH 7.5.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

N/A.

保存条件 & 期限

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

运输条件

Shipping with dry ice.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
C-MPL Protein, Cynomolgus (HEK293, His)
目录号:
HY-P700977
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