CHODL 蛋白, Mouse (HEK293, His)

CHODL proteins contribute significantly to nervous system development, particularly in neurite growth and elongation. There is evidence that it is involved in guiding motor axon growth and shaping the structural framework of the nervous system. CHODL Protein, Mouse (HEK293, His) is the recombinant mouse-derived CHODL protein, expressed by HEK293 , with C-His labeled tag.

CHODL 蛋白似乎是神经系统发育的复杂过程的重要贡献者，特别是在神经突生长和伸长领域。有证据表明它可能参与引导运动轴突生长，强调其在塑造神经系统结构框架中的作用。通过与 RABGGTB 等蛋白质的相互作用，CHODL 可能参与影响轴突发育和导航的复杂分子机制。对 CHODL 功能的全面了解，特别是其对神经突动力学和运动轴突引导的影响，有望揭示神经发育的关键方面，并可能有助于深入了解针对神经系统疾病的治疗策略。

Measured by its binding ability in a functional ELISA. When Recombinant Mouse CHODL Protein is immobilized at 1µg/mL (100 µL/well) can bind Recombinant Human IGFBP-5. The ED₅₀ for this effect is 29.56 ng/mL.

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  Measured by its binding ability in a functional ELISA. When Recombinant Mouse CHODL Protein is immobilized at 1µg/mL (100 µL/well) can bind Recombinant Human IGFBP-5. The ED₅₀ for this effect is 29.56 ng/mL.

Mouse

HEK293

C-6*His

Q9CXM0 (R22-N216)

246048  [NCBI]

RRVVSGQKVCFADVKHPCYKMAYFHELSSRVSFQEARLACESEGGVLLSLENEAEQKLIESMLQNLTKPGTGISDGDFWIGLLRSGDGQTSGACPDLYQWSDGSSSQFRNWYTDEPSCGSEKCVVMYHQPTANPGLGGPYLYQWNDDRCNMKHNYICKYEPEIHPTEPAEKPYLTNQPEETHENVVVTEAGIIPN

Approximately 30-33 kDa due to the glycosylation.

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  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.