Cyclophilin B/PPIB 蛋白, Human (HEK293, C-His, solution)

Cyclophilin B/PPIB protein is a peptidyl prolyl cis-trans isomerase (PPIase) that catalyzes the cis-trans isomerization of proline imide peptide bonds and may contribute to protein folding. This important enzymatic role highlights its importance in ensuring appropriate conformational changes in polypeptide chains, which are critical for functional maturation. Cyclophilin B/PPIB Protein, Human (HEK293, C-His, solution) is the recombinant human-derived Cyclophilin B/PPIB protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Cyclophilin B/PPIB Protein, Human (HEK293, C-His, solution) is 179 a.a., with molecular weight of ~21.0 kDa.

Cyclophilin B/PPIB 蛋白作为肽基脯氨酰顺反异构酶 (PPIase)，积极参与寡肽中脯氨酸酰亚胺肽键顺反异构化的催化，从而可能有助于促进蛋白质折叠。这种酶功能强调了蛋白质在促进多肽链适当构象变化的动态过程中的作用，这对于其功能成熟至关重要。作为复杂的蛋白质折叠领域的关键参与者，亲环蛋白 B/PPIB 通过促进新生或错误折叠多肽的正确折叠，在维持细胞蛋白质稳态中发挥着至关重要的作用。这些 PPIase 活性的精确协调强调了该蛋白质在细胞生理学中的重要性，需要进一步探索以揭示亲环蛋白 B/PPIB 促进蛋白质折叠动力学的特定分子机制和细胞途径。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

HEK293

C-6*His

P23284 (D34-A212)

5479  [NCBI]

DEKKKGPKVTVKVYFDLRIGDEDVGRVIFGLFGKTVPKTVDNFVALATGEKGFGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTVKTAWLDGKHVVFGKVLEGMEVVRKVESTKTDSRDKPLKDVIIADCGKIEVEKPFA

Approximately 21.0 kDa

Greater than 95% as determined by reducing SDS-PAGE

溶液.

Supplied as a 0.2 μm filtered solution of 20 mM PB, 6% Sucrose, 4% Mannitol, 50 mM NaCl, 0.05% Tween 80, pH 6.0.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.