2. Metabolic Enzyme/Protease
  3. Proteasome
  4. RID-F

RID-F (Ridaifen-F) 是一种 Tamoxifen (HY-13757A) 衍生物，是一种非肽类蛋白酶体抑制剂。RID-F 在亚微摩尔水平上抑制蛋白酶体的所有三种蛋白酶活性。

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RID-F Chemical Structure

RID-F Chemical Structure

CAS No. : 1020853-03-5

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规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

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RID-F 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

RID-F (Ridaifen-F), a Tamoxifen (HY-13757A) derivative, is a nonpeptidic proteasome inhibitor. RID-F inhibits human 20S proteasome activity, with IC50s of 0.64, 0.34, and 0.43 μM for CT-L, T-L, and PGPH, respectively[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HEK293 CC50
4.38 μM
Compound: 6, RID-F, Ridaifen-F
Cytotoxicity against ER-negative HEK293 cells after 48 hrs by MTT assay
Cytotoxicity against ER-negative HEK293 cells after 48 hrs by MTT assay
[PMID: 24321833]
HL-60 CC50
3.42 μM
Compound: 6, RID-F, Ridaifen-F
Cytotoxicity against ER-positive human HL60 cells after 48 hrs by MTT assay
Cytotoxicity against ER-positive human HL60 cells after 48 hrs by MTT assay
[PMID: 24321833]
RPMI-8226 CC50
3.6 μM
Compound: 1
Cytotoxicity against human RPMI8226 cells after 24 to 48 hrs by CellTiter-Glo assay
Cytotoxicity against human RPMI8226 cells after 24 to 48 hrs by CellTiter-Glo assay
[PMID: 29407987]
分子量

566.82

Formula

C38H50N2O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

RID-F 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RID-F1020853-03-5Ridaifen-FProteasomeInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-113824
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