2. GPCR/G Protein
  3. Endothelin Receptor
  4. Sarafotoxin S6c

Sarafotoxin S6c  (Synonyms: SRTX-c)

目录号: HY-102029 纯度: 98.19%
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摩尔计算器

Sarafotoxin S6c (SRTX-c) 是一种有效的内皮素B受体 (endothelin-B receptor) 激动剂。Sarafotoxin S6c 可引起内皮完好血管和内皮剥离血管的收缩。

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Custom Peptide Synthesis

Sarafotoxin S6c Chemical Structure

Sarafotoxin S6c Chemical Structure

CAS No. : 121695-87-2

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规格 价格 是否有货 数量
1 mg ￥1800
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5 mg ￥4500
In-stock
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Sarafotoxin S6c 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Sarafotoxin S6c (SRTX-c) is a potent endothelin-B receptor agonist. Sarafotoxin S6c can cause vasoconstriction in both endothelium-intact and endothelium-denuded vessels[1].

IC50 & Target

Endothelin-B receptor[1]
体内研究
(In Vivo)

Sarafotoxin S6c can cause vasoconstriction in both endothelium-intact and endothelium-denuded vessels[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Wister rats, exposed to 10% O2 [chronic hypoxic (CH) rats] or room air (control rats) for 2 weeks[1]
Dosage: 1 pM-1 mM
Administration:
Result: Chronic hypoxia had effect on the sensitivity of the main pulmonary arteries to SCS6c, and small vasoconstrictor responses to were evident.
Caused vasoconstriction with a maximum response 30% of that to ET-1 in both endothelium-intact and endothelium-denuded vessels.
分子量

2515.75

Formula

C103H147N27O37S5
CAS 号
性状

固体

颜色

White to off-white

Sequence Shortening

CTCNDMTDEECLNFCHQDVIW (Disulfide bridge: Cys1-Cys15; Cys3-Cys11)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

纯度 & 产品资料
参考文献

Sarafotoxin S6c 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sarafotoxin S6c121695-87-2SRTX-cEndothelin ReceptorInhibitorinhibitorinhibit

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目录号：
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