2. Cell Cycle/DNA Damage Epigenetics
  3. PARP
  4. ST7710AA1

T7710AA1 (compound 1l) 是一种有效的 PARP-1 抑制剂，其 IC50 值为 0.07 µM。ST7710AA1 表现出抗增殖活性。ST7710AA1 表现出抗癌活性。

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ST7710AA1 Chemical Structure

ST7710AA1 Chemical Structure

CAS No. : 1542067-20-8

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ST7710AA1 相关抗体

Top Publications Citing Use of Products

查看 PARP 亚型特异性产品:

查看所有亚型
PARP PARP1 PARP2 PARP3 PARP4 TNKS1/PARP5A TNKS2/PARP5B PARP7 PARP10 PARP14 PARP15 PARP12 PARP16

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

ST7710AA1 (compound 1l) is a potent PARP-1 inhibitor with an IC50 value of 0.07 µM. ST7710AA1 shows an antiproliferative activity. ST7710AA1 shows anticancer activity[1].

IC50 & Target[1]

PARP-1

0.07 μM (IC50)

体外研究
(In Vitro)

ST7710AA1 (compound 1l) (0-200 µM; 72 h) 表现出抗增殖作用，对 HCC1937、Capan 1 细胞的 IC50 值分别为 19.43、22.04 µM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

ST7710AA1 相关抗体:
体内研究
(In Vivo)

ST7710AA1 (100 mg/kg; i.p.; every 2 days for 2 weeks) 在小鼠中显示出抗肿瘤活性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

334.41

Formula

C20H22N4O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

ST7710AA1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ST7710AA11542067-20-8PARPpoly ADP ribose polymeraseHCC1937Capan 1antiproliferativeanticancerInhibitorinhibitorinhibit

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产品名称：
ST7710AA1
目录号：
HY-117423
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