2. Cell Cycle/DNA Damage
  3. DNA/RNA Synthesis
  4. Trenimon

Trenimon 是一种具有抗癌效应的化合物。Trenimon 通过诱导点突变和染色体突变、姐妹染色单体交换、重组现象和噬菌体诱导，在多种物种中具有诱变作用。Trenimon 可用于癌症的研究。

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Trenimon Chemical Structure

Trenimon Chemical Structure

CAS No. : 68-76-8

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Trenimon 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Trenimon is a compound with anti-cancer effects. Trenimon shows mutagenic actions in many species by inducing point and chromosomal mutations, sister-chromatid exchanges, recombination phenomena and phage induction. Trenimon can be used for the research of cancer[1][2][3][4].

体外研究
(In Vitro)

Trenimon (0.17 mM) penetrates readily into mouse lymphoma cells in vitro[1].
Trenimon (0.17 nM; 5 min-16 h) time-denpendently reduces the priming activity of DNA[2].
Trenimon (1 nM-10 μM; 10-20 min) leds HeLa cells death after 2 weeks with a dose of 10 μM and dose-dependently suppresses mitosis in cells[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Trenimon 相关抗体:
体内研究
(In Vivo)

Trenimon (0.25 mg/kg; i.p. once) rapidly depresseas of the cellular elements of the peripheral blood (granulocytes, lymphocytes, reticulocytes, platelets and erythrocytes), and reduces the cell number of bone marrow[4].
Trenimon (0.03 mg/kg; i.v. once per week for 52 weeks) shows an cancerogenic effect in vivo[4].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: BR 46 male rats[4]
Dosage: 0.03 mg/kg
Administration: Intravenous injection; 0.03 mg/kg once per week for 52 weeks
Result: Showed an cancerogenic effect and 24% animals developed malign tumors, and showed a induction time of the tumors is 16 months.
分子量

231.25

Formula

C12H13N3O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Trenimon 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Trenimon68-76-8DNA/RNA Synthesisanti-cancermutagenicratmitosislymphoma cellsInhibitorinhibitorinhibit

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