2. NF-κB
  3. NF-κB
  4. 11-Hydroxytephrosin

11-Hydroxytephrosin 是一种有效的 NF-kappaB 抑制剂。已知 NF-kappaB 在调节控制免疫系统、细胞凋亡 (apoptosis)、肿瘤细胞生长和组织分化的基因中发挥关键作用。

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11-Hydroxytephrosin Chemical Structure

11-Hydroxytephrosin Chemical Structure

CAS No. : 72458-85-6

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规格 价格 是否有货 数量
1 mg ￥4750
1 - 2 周
5 mg 现货 1 - 2 周
10 mg   询价  
50 mg   询价  

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11-Hydroxytephrosin 相关抗体

Top Publications Citing Use of Products

查看 NF-κB 亚型特异性产品:

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NF-κB NF-κB1/p50 RelA/p65 RelB c-Rel

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

11-Hydroxytephrosin is a potent inhibitor of NF-kappaB. NF-kappaB is known to play a crucial role in the regulation of genes controlling the immune system, apoptosis, tumor cell growth, and tissue differentiation[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HeLa IC50
0.19 μM
Compound: 2
Inhibition of TNF-alpha-induced NF-kappaB activation in human HeLa cells by SEAP reporter gene assay
Inhibition of TNF-alpha-induced NF-kappaB activation in human HeLa cells by SEAP reporter gene assay
[PMID: 18841906]
RAW264.7 IC50
4.21 μM
Compound: 2
Inhibition of LPS-induced NF-kappaB activation in mouse RAW264.7 cells by SEAP reporter gene assay
Inhibition of LPS-induced NF-kappaB activation in mouse RAW264.7 cells by SEAP reporter gene assay
[PMID: 18841906]
分子量

426.42

Formula

C23H22O8
CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

纯度 & 产品资料

纯度: ≥98.0%

COA (291 KB)

产品使用指南 (1538 KB)
参考文献

11-Hydroxytephrosin 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

11-Hydroxytephrosin72458-85-6NF-κBNuclear factor-κBNuclear factor-kappaBNF-kappaBimmune systemapoptosistumor cell growthtissue differentiationInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-N1022
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