2. Immunology/Inflammation
  3. Nuclear Factor of activated T Cells (NFAT)
  4. 11R-VIVIT

11R-VIVIT  (Synonyms: Cell permeable NFAT inhibitor)

目录号: HY-P1430
产品使用指南

摩尔计算器

11R-VIVIT 是一种活化 T 细胞的细胞通透性核因子 (NFAT) 抑制剂。11R-VIVIT 可用于足细胞和糖尿病肾病的研究。

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Custom Peptide Synthesis

11R-VIVIT Chemical Structure

11R-VIVIT Chemical Structure

CAS No. : 592517-80-1

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11R-VIVIT 的其他形式现货产品:

Customer Review

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11R-VIVIT 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

11R-VIVIT is a cell-permeable nuclear factor of activated T cells (NFAT) inhibitor. 11R-VIVIT can be used for the research of podocyte and diabetic nephropathy[1].

IC50 & Target

NFAT[1]
体外研究
(In Vitro)

11R-VIVIT (100 nM) shows a significant reduction of NFAT2 expression in high glucose treated podocytes compared to podocytes treated with normal glucose. 11R-VIVIT attenuates high glucose induced filtration barrier dysfunction of podocytes[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

11R-VIVIT 相关抗体:
体内研究
(In Vivo)

11R-VIVIT significantly abrogates the increased urinary albumin excretion rates, attenuates glomerular basement membrane (GBM) thickening and podocyte foot process effacement, partially restores podocyte number, inhibits NFAT2 activation and uPAR expression in glomerular podocytes[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

3573.15

Formula

C147H259N67O36S
CAS 号
Sequence Shortening

RRRRRRRRRRRGGGMAGPHPVIVITGPHEE
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

11R-VIVIT 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

11R-VIVIT592517-80-1Cell permeable NFAT inhibitorNuclear Factor of activated T Cells (NFAT)cell-permeablenuclearactivatedglucosefiltrationbarrierdysfunctionpodocytesInhibitorinhibitorinhibit

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