2. Metabolic Enzyme/Protease
  3. 11β-HSD
  4. 11β-HSD1-IN-9

11β-HSD1-IN-9 (化合物 c4a) 是一种有效的 11β-HSD1 抑制剂，对人源和鼠源 11β-HSD1 的 IC50 值分别为 0.48 和 1.3 µM。11β-HSD1-IN-9 与大鼠 11β-HSD1 有竞争性的相互作用。11β-HSD1-IN-19 可用于肥胖、高血糖和认知障碍的研究。

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11β-HSD1-IN-9 Chemical Structure

11β-HSD1-IN-9 Chemical Structure

CAS No. : 88283-34-5

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11β-HSD1-IN-9 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

11β-HSD1-IN-9 (compound c4a) is a potent 11β-HSD1 inhibitor with IC50 values of 0.48 and 1.3 µM for human and murine 11β-HSD1, respectively. 11β-HSD1-IN-9 competitively interacts with rat 11β-HSD1. 11β-HSD1-IN-19 can be used in studies of obesity, hyperglycemia and cognitive impairment[1].

分子量

266.22

Formula

C13H9F3N2O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

11β-HSD1-IN-9 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

11β-HSD1-IN-988283-34-511β-HSD11beta-HSD11β-hydroxysteroid dehydrogenases11 beta-hydroxysteroid dehydrogenaseglucocorticoidsobesityhyperglycemiacognitive impairmentInhibitorinhibitorinhibit

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