2. GPCR/G Protein
  3. Prostaglandin Receptor
  4. 12(S)-HPEPE

12(S)-HPEPE 是脂氧合酶产物和导致 PGHS-2 下调的中间代谢产物，具有潜在抗炎活性。12(S)-HPEPE 可降低人肺微血管内皮细胞中白细胞介素 1h (IL-1h) 诱导的 PGHS-2 表达。

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12(S)-HPEPE Chemical Structure

12(S)-HPEPE Chemical Structure

CAS No. : 103239-14-1

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12(S)-HPEPE 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

12(S)-HPEPE is a lipoxygenase product and an intermediate metabolite that leads to downregulation of PGHS-2 and has potential anti-inflammatory activity. 12(S)-HPEPE reduces interleukin 1h (IL-1h)-induced PGHS-2 expression in human lung microvascular endothelial cells[1].

IC50 & Target

PGHS-2[1]
分子量

334.45

Formula

C20H30O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

12(S)-HPEPE 相关分类

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  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

12(S)-HPEPE103239-14-1Prostaglandin ReceptorPGHS-2lipoxygenase producthuman lung microvascular endothelial cellsInhibitorinhibitorinhibit

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目录号：
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