2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. 14,15-Epoxyeicosatrienoic acid

14,15-Epoxyeicosatrienoic acid  (Synonyms: 14,15-EET)

目录号: HY-113489
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摩尔计算器

14,15-环氧二十碳三烯酸 (14,15-EET) 是花生四烯酸 (HY-109590) 的代谢产物。14,15-Epoxyeicosatrienoic acid 是一种有效的体内血小板聚集抑制剂。14,15-Epoxyeicosatrienoic acid 促进星形胶质细胞 Aβ 清除。14,15-Epoxyeicosatrienoic acid 可用于老年痴呆症的研究。

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14,15-Epoxyeicosatrienoic acid Chemical Structure

14,15-Epoxyeicosatrienoic acid Chemical Structure

CAS No. : 81276-03-1

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规格 价格 是否有货 数量
50 μg（312.04 μM * 500 μL in Ethanol） ￥5600
1 - 2 周

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14,15-Epoxyeicosatrienoic acid 相关抗体

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  • 生物活性

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生物活性

14,15-Epoxyeicosatrienoic acid (14,15-EET) is a metabolite of Arachidonic acid (HY-109590). 14,15-Epoxyeicosatrienoic acid is a potent inhibitor of in vivo platelet aggregation. 14,15-Epoxyeicosatrienoic acid facilitates astrocytic Aβ clearance. 14,15-Epoxyeicosatrienoic acid can be used for Alzheimer's Disease research[1][2].

IC50 & Target

Human Endogenous Metabolite

 

体外研究
(In Vitro)

14,15-Epoxyeicosatrienoic acid (0-10 μM) 促进原代星形胶质细胞培养物中的 Aβ 摄取[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

14,15-Epoxyeicosatrienoic acid 相关抗体:
体内研究
(In Vivo)

14,15-Epoxyeicosatrienoic acid (0.3 mg/kg i.v.) 可抑制小鼠脑小动脉中的血小板聚集[2]。
14,15-Epoxyeicosatrienoic acid (200 ng/ml) 注入海马体可逆转 6 个月大的雄性 FAD 小鼠大脑中的 Aβ 沉积[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

320.47

Formula

C20H32O3
CAS 号
性状

液体（密度：0.983±0.06 g/cm3）

颜色

Colorless to light yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥99.0%

COA (184 KB)

产品使用指南 (1538 KB)
参考文献

14,15-Epoxyeicosatrienoic acid 相关分类

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Keywords:

14,15-Epoxyeicosatrienoic acid81276-03-114,15-EETEndogenous MetaboliteAlzheimer's diseaseastrocytelysosomal biogenesissoluble epoxide hydrolaseInhibitorinhibitorinhibit

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