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2',4'-Dihydroxy-4,6'-diMethoxydihydrochalcone 

目录号: HY-N8796
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2',4'-Dihydroxy-4,6'-diMethoxydihydrochalcone 是一种从 Iryanthera juruensis Warb 中分离得到的二氢查耳酮化合物。在针对一组癌细胞系进行测试时，2',4'-Dihydroxy-4,6'-diMethoxydihydrochalcone 是一种主要的细胞毒性代谢物。

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2',4'-Dihydroxy-4,6'-diMethoxydihydrochalcone Chemical Structure

2',4'-Dihydroxy-4,6'-diMethoxydihydrochalcone Chemical Structure

CAS No. : 75679-58-2

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2',4'-Dihydroxy-4,6'-diMethoxydihydrochalcone 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

2',4'-Dihydroxy-4,6'-diMethoxydihydrochalcone is a dihydrochalcone compound isolated from Iryanthera juruensis Warb. 2',4'-Dihydroxy-4,6'-diMethoxydihydrochalcone is a major cytotoxic metabolite when tested against a panel of cancer cell lines[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
DU-145 GI50
> 206 μM
Compound: 1
Cytotoxicity against human DU145 cells after 48 hrs
Cytotoxicity against human DU145 cells after 48 hrs
[PMID: 18798609]
HT-29 GI50
> 206 μM
Compound: 1
Cytotoxicity against human HT29 cells after 48 hrs
Cytotoxicity against human HT29 cells after 48 hrs
[PMID: 18798609]
K562 GI50
22.8 μM
Compound: 1
Cytotoxicity against human K562 cells after 48 hrs
Cytotoxicity against human K562 cells after 48 hrs
[PMID: 18798609]
M14 GI50
109.2 μM
Compound: 1
Cytotoxicity against human M14 cells after 48 hrs
Cytotoxicity against human M14 cells after 48 hrs
[PMID: 18798609]
MCF7 GI50
65.5 μM
Compound: 1
Cytotoxicity against human MCF7 cells after 48 hrs
Cytotoxicity against human MCF7 cells after 48 hrs
[PMID: 18798609]
NCI-H460 GI50
128 μM
Compound: 1
Cytotoxicity against human H460 cells after 48 hrs
Cytotoxicity against human H460 cells after 48 hrs
[PMID: 18798609]
NIH3T3 GI50
> 206 μM
Compound: 1
Cytotoxicity against BALB mouse 3T3 cells after 48 hrs
Cytotoxicity against BALB mouse 3T3 cells after 48 hrs
[PMID: 18798609]
PC-3 GI50
59.9 μM
Compound: 1
Cytotoxicity against human PC3 cells after 48 hrs
Cytotoxicity against human PC3 cells after 48 hrs
[PMID: 18798609]
Vero IC50
> 25 μM
Compound: 1
Antitrypanosomal activity against Trypanosoma cruzi Tulahuen C4 in african green monkey Vero cells after 120 hrs
Antitrypanosomal activity against Trypanosoma cruzi Tulahuen C4 in african green monkey Vero cells after 120 hrs
[PMID: 18798609]
分子量

302.32

Formula

C17H18O5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

2',4'-Dihydroxy-4,6'-diMethoxydihydrochalcone 相关分类

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质量   浓度   体积   分子量 *
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2',4'-Dihydroxy-4,6'-diMethoxydihydrochalcone75679-58-2Othersdihydrochalconecytotoxic metabolitecancerInhibitorinhibitorinhibit

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