2. Anti-infection
  3. Bacterial
  4. 2'-​Hydroxy-​2-​methoxychalcone

2'-​Hydroxy-​2-​methoxychalcone 

目录号: HY-128452
产品使用指南 技术支持

2'-Hydroxy-2-methoxychalcone (compound 3b) 是一个合成的查尔酮，具有抗菌活性。

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2'-​Hydroxy-​2-​methoxychalcone Chemical Structure

2'-​Hydroxy-​2-​methoxychalcone Chemical Structure

CAS No. : 42220-77-9

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2'-​Hydroxy-​2-​methoxychalcone 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

2'-Hydroxy-2-methoxychalcone (compound 3b) is a synthetic chalcone, with antimicrobial activity[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A2780cisR GI50
11.69 μM
Compound: 1
Growth inhibition of cisplatin-resistant human A2780cis cells after 7 days by crystal violet staining based clonogenic assay
Growth inhibition of cisplatin-resistant human A2780cis cells after 7 days by crystal violet staining based clonogenic assay
[PMID: 24565968]
CHO IC50
25.5 μM
Compound: 8a
Cytotoxicity against CHO cells assessed as decrease in cell proliferation after 48 hrs by MTS assay
Cytotoxicity against CHO cells assessed as decrease in cell proliferation after 48 hrs by MTS assay
[PMID: 27161874]
CHO IC50
25.5 μM
Compound: 8a
Cytotoxicity against CHO cells after 48 hrs by MTS assay
Cytotoxicity against CHO cells after 48 hrs by MTS assay
[PMID: 23768434]
HEK-293T EC50
1.4 μM
Compound: 8a
Inverse agonist activity at human cytomegalovirus US28 receptor transfected in HEK293T cells assessed as activation of MAPK signaling pathway after 20 to 24 hrs by luciferase-based Elk1 reporter gene assay
Inverse agonist activity at human cytomegalovirus US28 receptor transfected in HEK293T cells assessed as activation of MAPK signaling pathway after 20 to 24 hrs by luciferase-based Elk1 reporter gene assay
[PMID: 23768434]
分子量

254.28

Formula

C16H14O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

2'-​Hydroxy-​2-​methoxychalcone 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2'-​Hydroxy-​2-​methoxychalcone42220-77-9BacterialInhibitorinhibitorinhibit

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