1. Metabolic Enzyme/Protease
  2. HIV Integrase
  3. 2-Hydroxyisoquinoline-1,3(2H,4H)-dione

2-Hydroxyisoquinoline-1,3(2H,4H)-dione 

目录号: HY-W103287
产品使用指南

Hydroxyisoquinoline-1,3(2H,4H)-dione (compound 6a) 是 HIV-1 整合酶 (HIV-1 integrase (IN)) 和 HIV-1 逆转录酶核糖核酸酶 H (HIV-1 reverse transcriptase (RT) ribonuclease H (RNase H)) 抑制剂,IC50 值分别为 6.32、5.9 µM。

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2-Hydroxyisoquinoline-1,3(2H,4H)-dione Chemical Structure

2-Hydroxyisoquinoline-1,3(2H,4H)-dione Chemical Structure

CAS No. : 6890-08-0

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Hydroxyisoquinoline-1,3(2H,4H)-dione (compound 6a) is a HIV-1 integrase (IN) and HIV-1 reverse transcriptase (RT) ribonuclease H (RNase H) inhibitor with an IC50 value of 6.32, 5.9 µM, respectively[1].

IC50 & Target

IC50: 6.32 µM (HIV-1 IN); 5.9 µM (HIV-1 RT RNase H)[1]

分子量

177.16

Formula

C9H7NO3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

2-Hydroxyisoquinoline-1,3(2H,4H)-dione 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
2-Hydroxyisoquinoline-1,3(2H,4H)-dione
目录号:
HY-W103287
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