1. Apoptosis
  2. Apoptosis
  3. 27-TBDMS-4-Dehydrowithaferin A

27-TBDMS-4-Dehydrowithaferin A 

目录号: HY-N10355
产品使用指南

27-TBDMS-4-Dehydrowithaferin A 是一种叶黄素 A 衍生物,对肿瘤细胞具有强大的抗增殖作用。27-TBDMS-4-Dehydrowithaferin A 诱导肿瘤细胞凋亡。27-TBDMS-4-Dehydrowithaferin A 是一种抗癌剂。

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27-TBDMS-4-Dehydrowithaferin A Chemical Structure

27-TBDMS-4-Dehydrowithaferin A Chemical Structure

CAS No. : 1214886-31-3

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规格 价格 是否有货 数量
1 mg ¥1706
3 - 4 周
5 mg   询价  
10 mg   询价  

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

27-TBDMS-4-Dehydrowithaferin A, a withaferin A derivative, exhibits potent antiproliferative effects on the tumor cells.27-TBDMS-4-Dehydrowithaferin A induces tumor cells apoptosis. 27-TBDMS-4-Dehydrowithaferin A is a anticancer agent[1].

体外研究
(In Vitro)

27-TBDMS-4-Dehydrowithaferin A (compound 9b; 48 h) exhibits potent antiproliferative effects on HeLa (IC50=1.7 μM), A-549 (IC50=5.3 μM), MCF-7 (IC50=0.5 μM), and normal Vero cells (IC50=3.1 μM)[1].
27-TBDMS-4-Dehydrowithaferin A (24 μM; 48 h) activates caspase-3 in HeLa cells[1].
27-TBDMS-4-Dehydrowithaferin A (8 μM; 1-4 h) with a longer incubation period (2-4 h) leads to apoptosis, effect that was maintained at concentrations of 12 and 16 μM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

582.84

Formula

C34H50O6Si

CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
27-TBDMS-4-Dehydrowithaferin A
目录号:
HY-N10355
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