1. Autophagy
  2. Autophagy
  3. 2G-HaloAUTAC

2G-HaloAUTAC (Compound tt44) 是第二代自噬靶向嵌合体 (2G-HaloAUTAC),通过用其他结构替换L-半胱氨酸 (L-Cys) 连接子来提高自噬靶向嵌合体 (AUTAC) 的活性。2G-HaloAUTAC 通过自噬机制表现出针对 EGFP-HaloTag 蛋白的降解活性。

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2G-HaloAUTAC Chemical Structure

2G-HaloAUTAC Chemical Structure

CAS No. : 2241668-58-4

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

2G-HaloAUTAC (Compound tt44) is a second-generation autophagy-targeting chimera (2G-HaloAUTAC) that improves the activity of AUTACs by replacing the L-Cysteine ​​(L-Cys) linker with other structures. 2G-HaloAUTAC exhibits degradation activity against EGFP-HaloTag protein through an autophagic mechanism[1].

分子量

664.17

Formula

C31H43ClFN7O6

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

2G-HaloAUTAC 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
2G-HaloAUTAC
目录号:
HY-160902
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