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  5. 3β-Methoxy-2,3-dihydrowithaferin A

3β-Methoxy-2,3-dihydrowithaferin A  (Synonyms: Quresimin A)

目录号: HY-N5131
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摩尔计算器

3β-Methoxy-2,3-dihydrowithaferin A 是存在于南非醉茄中的一种醉茄内脂类天然产物。

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3β-Methoxy-2,3-dihydrowithaferin A Chemical Structure

3β-Methoxy-2,3-dihydrowithaferin A Chemical Structure

CAS No. : 73365-94-3

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3β-Methoxy-2,3-dihydrowithaferin A 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

3β-Methoxy-2,3-dihydrowithaferin A is one of withanolides found in Withania somnifera[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
> 40 μM
Compound: 44
Cytotoxicity against human A549 cells assessed as reduction in cell viability using compound addition to cell culture cells in lag phase of growth and incubated for 48 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as reduction in cell viability using compound addition to cell culture cells in lag phase of growth and incubated for 48 hrs by MTT assay
[PMID: 28923386]
A549 IC50
> 40 μM
Compound: 44
Cytotoxicity against human A549 cells assessed as reduction in cell viability using compound addition to cell culture cells in log phase of growth and incubated for 48 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as reduction in cell viability using compound addition to cell culture cells in log phase of growth and incubated for 48 hrs by MTT assay
[PMID: 28923386]
B16-F10 IC50
> 10 μM
Compound: 17
Cytotoxicity against mouse B16F10 cells after 72 hrs by MTS assay
Cytotoxicity against mouse B16F10 cells after 72 hrs by MTS assay
[PMID: 22098611]
C3H 10T1/2 IC50
> 25 μM
Compound: 5
Cytotoxicity against mouse C3H10T1/2 cells after 24 hrs by FMCA
Cytotoxicity against mouse C3H10T1/2 cells after 24 hrs by FMCA
[PMID: 26169123]
DU-145 IC50
> 25 μM
Compound: 5
Cytotoxicity against human DU145 cells after 24 hrs by FMCA
Cytotoxicity against human DU145 cells after 24 hrs by FMCA
[PMID: 26169123]
HaCaT IC50
> 25 μM
Compound: 5
Inhibition of hedgehog/GLI1-mediated transcriptional activity in human HaCaT cells after 12 hrs by luciferase assay
Inhibition of hedgehog/GLI1-mediated transcriptional activity in human HaCaT cells after 12 hrs by luciferase assay
[PMID: 26169123]
HeLa IC50
> 40 μM
Compound: 44
Cytotoxicity against human HeLa cells assessed as reduction in cell viability using compound addition to cell culture cells in lag phase of growth and incubated for 48 hrs by MTT assay
Cytotoxicity against human HeLa cells assessed as reduction in cell viability using compound addition to cell culture cells in lag phase of growth and incubated for 48 hrs by MTT assay
[PMID: 28923386]
HeLa IC50
> 40 μM
Compound: 44
Cytotoxicity against human HeLa cells assessed as reduction in cell viability using compound addition to cell culture cells in log phase of growth and incubated for 48 hrs by MTT assay
Cytotoxicity against human HeLa cells assessed as reduction in cell viability using compound addition to cell culture cells in log phase of growth and incubated for 48 hrs by MTT assay
[PMID: 28923386]
MCF7 IC50
> 25 μM
Compound: 5
Cytotoxicity against human MCF7 cells after 24 hrs by FMCA
Cytotoxicity against human MCF7 cells after 24 hrs by FMCA
[PMID: 26169123]
MCF7 IC50
> 40 μM
Compound: 44
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability using compound addition to cell culture cells in lag phase of growth and incubated for 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability using compound addition to cell culture cells in lag phase of growth and incubated for 48 hrs by MTT assay
[PMID: 28923386]
MCF7 IC50
> 40 μM
Compound: 44
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability using compound addition to cell culture cells in log phase of growth and incubated for 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability using compound addition to cell culture cells in log phase of growth and incubated for 48 hrs by MTT assay
[PMID: 28923386]
PANC-1 IC50
> 25 μM
Compound: 5
Cytotoxicity against human PANC1 cells after 24 hrs by FMCA
Cytotoxicity against human PANC1 cells after 24 hrs by FMCA
[PMID: 26169123]
SK-MEL-28 IC50
> 10 μM
Compound: 17
Cytotoxicity against human SK-MEL-28 cells after 72 hrs by MTS assay
Cytotoxicity against human SK-MEL-28 cells after 72 hrs by MTS assay
[PMID: 22098611]
Vero IC50
> 40 μM
Compound: 44
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability using compound addition to cell culture cells in lag phase of growth and incubated for 48 hrs by MTT assay
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability using compound addition to cell culture cells in lag phase of growth and incubated for 48 hrs by MTT assay
[PMID: 28923386]
Vero IC50
> 40 μM
Compound: 44
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability using compound addition to cell culture cells in log phase of growth and incubated for 48 hrs by MTT assay
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability using compound addition to cell culture cells in log phase of growth and incubated for 48 hrs by MTT assay
[PMID: 28923386]
分子量

502.64

Formula

C29H42O7
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

3β-Methoxy-2,3-dihydrowithaferin A 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

3β-Methoxy-2,3-dihydrowithaferin A73365-94-3Quresimin AOthersInhibitorinhibitorinhibit

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