2. 天然产物
  3. 植物 苯丙素类
  4. 小檗科 木脂素
  5. 北美桃儿七
  6. 4'-Demethylpodophyllotoxone

4'-Demethylpodophyllotoxone 是链格孢 (lternaria alternata) S-f6 进行生物转化的中间产物。4'-Demethylpodophyllotoxone 经 4- (2,3,5,6-tetramethylpyrazine-1) (4-TMP) 修饰后，产生的新型化合物可强烈抑制人胃癌细胞系 (BGC-823) 的生长。

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4'-Demethylpodophyllotoxone Chemical Structure

4'-Demethylpodophyllotoxone Chemical Structure

CAS No. : 93780-84-8

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规格 价格 是否有货
1 mg ￥1200
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5 mg ￥3000
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4'-Demethylpodophyllotoxone 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

4'-Demethylpodophyllotoxone is an intermediate product of the biotransformation of Alternaria alternata S-f6. After 4'-Demethylpodophyllotoxone is modified with 4-(2,3,5,6-tetramethylpyrazine-1) (4-TMP), the resulting novel compound can strongly inhibit the growth of human gastric cancer cell line (BGC-823)[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
H9 EC50
0.8 μM
Compound: 16
Evaluation for anti-HIV activity using T cell line (H9).
Evaluation for anti-HIV activity using T cell line (H9).
10.1016/S0960-894X(97)10108-1
分子量

398.36

Formula

C21H18O8
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

4'-Demethylpodophyllotoxone 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4'-Demethylpodophyllotoxone93780-84-8OthersBiotransformation product heterogeneityBiotransformation metabolic pathwayYeast extractInhibitorinhibitorinhibit

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目录号：
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