2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. iGluR
  4. 5,7-Dichlorokynurenic acid sodium

5,7-Dichlorokynurenic acid sodium  (Synonyms: 5,7-DCKA sodium)

目录号: HY-100834A
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摩尔计算器

5,7-Dichlorokynurenic acid (sodium) 是 5,7-Dichlorokynurenic acid (HY-100834) 的钠盐形式。5,7-Dichlorokynurenic acid 是一种选择性的 NMDA 受体甘氨酸位点竞争性拮抗剂，KB 值为 65 nM。5,7-Dichlorokynurenic acid 是犬尿酸的衍生物，可减少大鼠皮质细胞培养物中 NMDA 诱导的神经元损伤。

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5,7-Dichlorokynurenic acid sodium Chemical Structure

5,7-Dichlorokynurenic acid sodium Chemical Structure

CAS No. : 1184986-70-6

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5,7-Dichlorokynurenic acid sodium 的其他形式现货产品:

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5,7-Dichlorokynurenic acid sodium 相关抗体

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生物活性

5,7-Dichlorokynurenic acid (sodium) is the sodium form of 5,7-Dichlorokynurenic acid (HY-100834). 5,7-Dichlorokynurenic acid is a selective and competitive antagonist of the glycine site on the NMDA receptor with a KB of 65 nM. 5,7-Dichlorokynurenic acid, a derivative of kynurenic acid, reduces NMDA-induced neuron injury in rat cortical cell cultures[1].

分子量

280.04

Formula

C10H4Cl2NNaO3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

5,7-Dichlorokynurenic acid sodium 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5,7-Dichlorokynurenic acid1184986-70-65,7-DCKAiGluRIonotropic glutamate receptorssodiumNMDAkynurenic acidderivativeneuron injuryInhibitorinhibitorinhibit

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