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  3. 5-Chloroisoquinoline

5-Chloroisoquinoline (compound 42) 是一种 SARM1 抑制剂,SARM1 (Sterile alpha and toll/interleukin receptor (TIR) motif containing protein 1) 是一种参与轴突变性的酶,它通过三元复合机制催化多种活性。5-Chloroisoquinoline 可用于神经退行性疾病或轴突变性的研究。

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5-Chloroisoquinoline Chemical Structure

5-Chloroisoquinoline Chemical Structure

CAS No. : 5430-45-5

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  • 生物活性

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生物活性

5-Chloroisoquinoline (compound 42) is an inhibitor of SARM1 (Sterile alpha and toll/interleukin receptor (TIR) motif containing protein 1), an enzyme involved in axon degeneration that catalyzes multiple activities through a ternary complex mechanism. 5-Chloroisoquinoline can be used in the study of neurodegenerative diseases or axon degeneration[1].

IC50 & Target

SARM1

分子量

163.60

Formula

C9H6ClN

CAS 号
性状

固体

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
纯度 & 产品资料
参考文献

5-Chloroisoquinoline 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
5-Chloroisoquinoline
目录号:
HY-W008341
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