2. Metabolic Enzyme/Protease Apoptosis
  3. Drug Metabolite Apoptosis
  4. 5-Hydroxydiclofenac

5-Hydroxydiclofenac 是 Diclofenac (HY-15036) 的主要代谢物。5-Hydroxydiclofenac 由细胞色素 P450 (CYP) 同工酶 CYP3A4、CYP2C189、CYP2C19 和 CYP2C8 形成。5-Hydroxydiclofenac 在肝细胞中表现出凋亡 (apoptosis) 作用。

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5-Hydroxydiclofenac Chemical Structure

5-Hydroxydiclofenac Chemical Structure

CAS No. : 69002-84-2

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5-Hydroxydiclofenac 相关抗体

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  • 生物活性

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生物活性

5-Hydroxydiclofenac is a major metabolite of Diclofenac (HY-15036). 5-Hydroxydiclofenac is formed by the cytochrome P450 (CYP) isoforms CYP3A4, CYP2C189, CYP2C19, and CYP2C8. 5-Hydroxydiclofenac shows apoptotic effects in hepatocytes[1].

分子量

312.15

Formula

C14H11Cl2NO3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

5-Hydroxydiclofenac 相关分类

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Keywords:

5-Hydroxydiclofenac69002-84-2Drug MetaboliteApoptosismetabolite of DiclofenacapoptosisCYP3A4CYP2C189CYP2C19CYP2C8Inhibitorinhibitorinhibit

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