2. Others
  3. Isotope-Labeled Compounds
  4. 6α-Hydroxy Paclitaxel-d5

6α-Hydroxy Paclitaxel-d5 

目录号: HY-125348S 纯度: 99.31%
COA 产品使用指南

摩尔计算器

6α-Hydroxy Paclitaxel-d5 是 6α-Hydroxy paclitaxel 的氘代物。6α-Hydroxy paclitaxel 是紫杉醇的初级代谢物。6α-Hydroxy paclitaxel 对有机阴离子转运多肽 1B1/SLCO1B1 (OATP1B1) 具有与紫杉醇相似的时间依赖性抑制效力，但它对 OATP1B3 不具有时间依赖性作用。6α-Hydroxy paclitaxel 可用于癌症研究。

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6α-Hydroxy Paclitaxel-d<sub>5</sub> Chemical Structure

6α-Hydroxy Paclitaxel-d5 Chemical Structure

CAS No. : 1315376-90-9

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1 mg ￥29000
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Other Forms of 6α-Hydroxy Paclitaxel-d5:

6α-Hydroxy Paclitaxel-d5 相关抗体

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  • 生物活性

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  • 参考文献

生物活性

6α-Hydroxy Paclitaxel-d5 is the deuterium labeled 6α-Hydroxy paclitaxel. 6α-Hydroxy paclitaxel is a primary metabolite of Paclitaxel. 6α-Hydroxy paclitaxel retains a time-dependent effect on organic anion–transporting polypeptides 1B1/SLCO1B1 (OATP1B1) with similar inhibition potency to Paclitaxel, whereas it no longer showed time-dependent inhibition of OATP1B3. 6α-Hydroxy paclitaxel can be used for the research of cancer[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

6α-Hydroxy Paclitaxel-d5 相关抗体:
分子量

874.94

Formula

C47H46D5NO15
CAS 号
非标记 CAS

153212-75-0
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献

6α-Hydroxy Paclitaxel-d5 相关分类

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Keywords:

6α-Hydroxy Paclitaxel-d51315376-90-9Isotope-Labeled CompoundsInhibitorinhibitorinhibit

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