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  4. 6-Amino-8-trifluoromethylphenanthridine

6-Amino-8-trifluoromethylphenanthridine  (Synonyms: 6A-8tFP)

目录号: HY-134561
产品使用指南

摩尔计算器

6-Amino-8-trifluoromethylphenanthridine (6A-8tFP) 是一种抗朊病毒剂，也是 6-氨基菲啶的衍生物。当使用浓度为 150 μM 时，它会抑制核糖体的蛋白质折叠活性 (PFAR)。6A-8tFP 直接与蛋白质底物竞争核糖体活性位点。

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6-Amino-8-trifluoromethylphenanthridine Chemical Structure

6-Amino-8-trifluoromethylphenanthridine Chemical Structure

CAS No. : 651055-83-3

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6-Amino-8-trifluoromethylphenanthridine 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

6-Amino-8-trifluoromethylphenanthridine (6A-8tFP) is an antiprion agent and a derivative of 6-aminophenanthridine (HY-135189). It inhibits protein folding activity of the ribosome (PFAR) when used at a concentration of 150 μM.2 6A-8tFP directly competes with protein substrates for the ribosomal active site.

分子量

262.23

Formula

C14H9F3N2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

6-Amino-8-trifluoromethylphenanthridine 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

6-Amino-8-trifluoromethylphenanthridine651055-83-36A-8tFPOthersInhibitorinhibitorinhibit

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