1. Apoptosis
  2. Apoptosis
  3. 6-Dehydrogingerdione

6-Dehydrogingerdione 通过活性氧介导 DR5 的增加,使人肝母细胞瘤 Hep G2 细胞对 TRAIL 诱导的凋亡敏感。

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6-Dehydrogingerdione Chemical Structure

6-Dehydrogingerdione Chemical Structure

CAS No. : 76060-35-0

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规格 价格 是否有货 数量
1 mg ¥1260
1 - 2 周
5 mg ¥3150
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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

6-Dehydrogingerdione sensitizes human hepatoblastoma Hep G2 cells to TRAIL-induced apoptosis via reactive oxygen species-mediated increase of DR5[1].

体外研究
(In Vitro)

6-Dehydrogingerdione could trigger apoptotic cell death via both mitochondrial- and Fas receptor-mediated pathways[1].
6-Dehydrogingerdione (6-DG) up-regulates Ser-15 phosphorylation and evoked p53 nuclear translocation[1].
6-Dehydrogingerdione (6-DG) induces mitochondrial apoptotic pathway[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Apoptosis Analysis[1]

Cell Line: Hep G2 cells.
Concentration: 0, 50, 100 μM.
Incubation Time: 24 h.
Result: Induced Apoptosis in Hep G2 Cells.
分子量

290.35

Formula

C17H22O4

CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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产品名称:
6-Dehydrogingerdione
目录号:
HY-N7152
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