1. Cell Cycle/DNA Damage Cytoskeleton
  2. Microtubule/Tubulin
  3. 7a-Hydroxyfrullanolide

7a-Hydroxyfrullanolide 具有抗癌特性。7a-Hydroxyfrullanolide 可降低 α-、β-微管蛋白的聚合。7a-Hydroxyfrullanolide 更倾向于与 β-微管蛋白结合,而不是 α-微管蛋白。7a-Hydroxyfrullanolide 还会触发 DNA 损伤反应,使细胞停滞在 G2/M 期。7a-Hydroxyfrullanolide 是一种桉树内酯倍半萜内酯 (SL),可从菊科开花植物中分离出来。

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7a-Hydroxyfrullanolide Chemical Structure

7a-Hydroxyfrullanolide Chemical Structure

CAS No. : 105578-87-8

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生物活性

7a-Hydroxyfrullanolide has anticancer properties. 7a-Hydroxyfrullanolide reduces polymerization of α-, β-tubulin. 7a-Hydroxyfrullanolide preferrs to bind to β-tubulin over α-tubulin. 7a-Hydroxyfrullanolide also triggers DNA damage response arrests cells in the G2/M-phase. 7a-Hydroxyfrullanolide is an eudesmanolide sesquiterpene lactone (SL) and can be isolated from the flowering plants of the Asteraceae family[1].

分子量

248.32

Formula

C15H20O3

CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

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产品名称:
7a-Hydroxyfrullanolide
目录号:
HY-W749442
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