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  3. 7α,24(S)-Dihydroxycholesterol

7α,24(S)-Dihydroxycholesterol  (Synonyms: (3β,7α,24S)-Cholest-5-ene-3,7,24-triol)

目录号: HY-133830
产品使用指南

7α,24(S)-Dihydroxycholesterol ((3β,7α,24S)-Cholest-5-ene-3,7,24-triol) 是肝X受体 (LXR) 的配体,可特异性结合 LXRα 和 LXRβ 的配体结合域。该化合物由 E-α,β-烯酮合成,利用砷叶立德和 J-叔丁基二甲基硅氧基-双正-5-胆烯醛作为起始材料,然后经过一系列转化生成 7α,24(S)-二羟基胆固醇。

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7α,24(S)-Dihydroxycholesterol Chemical Structure

7α,24(S)-Dihydroxycholesterol Chemical Structure

CAS No. : 245523-67-5

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  • 生物活性

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生物活性

7α,24(S)-Dihydroxycholesterol ((3β,7α,24S)-Cholest-5-ene-3,7,24-triol) serves as a ligand for liver X receptor (LXR), binding specifically to the ligand binding domains of both LXRα and LXRβ. This compound is synthetically produced from E-α,β-enone, utilizing Arsonium ylide and J-tert-butyldimethylsilyloxy-bisnor-5-cholenaldehyde as starting materials, followed by a series of transformations to yield 7α,24(S)-dihydroxycholesterol.

分子量

418.65

Formula

C27H46O3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料

7α,24(S)-Dihydroxycholesterol 相关分类

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产品名称:
7α,24(S)-Dihydroxycholesterol
目录号:
HY-133830
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